Evidence map›Paper›PMID 40076924›Full record

ArticleInternational journal of molecular sciences2025

Insight into the Relationships Between Chemical, Protein and Functional Variables in the PBP/GOBP Family in Moths Based on Machine Learning.

Xaviera A López-Cortés, Gabriel Lara, Nicolás Fernández, José M Manríquez-Troncoso, Herbert Venthur

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Xaviera A López-CortésDepartment of Computer Sciences and Industries, Universidad Católica del Maule, Talca 3466706, Chile.ORCID 0000-0002-7514-8777
Gabriel LaraCentro de Innovación en Ingeniería Aplicada (CIIA), Universidad Católica del Maule, Talca 3466706, Chile.
Nicolás FernándezCentro de Innovación en Ingeniería Aplicada (CIIA), Universidad Católica del Maule, Talca 3466706, Chile.
José M Manríquez-TroncosoCentro de Innovación en Ingeniería Aplicada (CIIA), Universidad Católica del Maule, Talca 3466706, Chile.
Herbert VenthurLaboratorio de Química Ecológica, Departamento de Ciencias Químicas y Recursos Naturales, Facultad de Ingenieria y Ciencias, Universidad de La Frontera, Temuco 4811230, Chile.ORCID 0000-0002-1083-758X

Funding

Agencia Nacional de Investigación y Desarrollo, Fondecyt Regular 1240459
6 · The paper itself

Abstract

During their lives, insects must cope with a plethora of chemicals, of which a few will have an impact at the behavioral level. To detect these chemicals, insects use several protein families located in their main olfactory organs, the antennae. Inside the antennae, odorant-binding proteins (OBPs), as the most studied protein family, bind volatile chemicals to transport them. Pheromone-binding proteins (PBPs) and general-odorant-binding proteins (GOPBs) are two subclasses of OBPs and have evolved in moths with a putative olfactory role. Predictions for OBP-chemical interactions have remained limited, and functional data collected over the years unused. In this study, chemical, protein and functional data were curated, and related datasets were created with descriptors. Regression algorithms were implemented and their performance evaluated. Our results indicate that XGBoostRegressor exhibits the best performance (

Indexed as

Carrier ProteinsInsect ProteinsMachine LearningMothsReceptors, OdorantAlgorithmsAnimalsCarrier ProteinsInsect Proteinsodorant-binding proteinpheromone binding protein, insectReceptors, Odorantartificial intelligencechemical ecologylepidopteraligand bindingodorant-binding proteinsregression algorithm

Identifiers

PMID40076924
PMCPMC11901117

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.