Evidence map›Paper›PMID 40076847›Full record

ArticleInternational journal of molecular sciences2025

Graphene-Based Far-Infrared Therapy Promotes Adipose Tissue Thermogenesis and UCP1 Activation to Combat Obesity in Mice.

Jinshui Zhang, Shuo Li, Xin Cheng, Xiaocui Tan, Yingxian Shi, Guixin Su, Yulong Huang, Yang Zhang, Rui Xue, Jingcao Li and 4 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Jinshui ZhangBeijing Institute of Pharmacology and Toxicology, Beijing 100850, China.
Shuo LiBeijing Institute of Pharmacology and Toxicology, Beijing 100850, China.
Xin ChengBeijing Institute of Pharmacology and Toxicology, Beijing 100850, China.
Xiaocui TanBeijing Institute of Pharmacology and Toxicology, Beijing 100850, China.
Yingxian ShiBeijing Institute of Pharmacology and Toxicology, Beijing 100850, China.
Guixin SuBeijing Institute of Pharmacology and Toxicology, Beijing 100850, China.
Yulong HuangBeijing Institute of Pharmacology and Toxicology, Beijing 100850, China.
Yang ZhangBeijing Institute of Pharmacology and Toxicology, Beijing 100850, China.
Rui XueBeijing Institute of Pharmacology and Toxicology, Beijing 100850, China.
Jingcao LiBeijing Institute of Pharmacology and Toxicology, Beijing 100850, China.
Qiongyin FanBeijing Institute of Pharmacology and Toxicology, Beijing 100850, China.
Huajin DongBeijing Institute of Pharmacology and Toxicology, Beijing 100850, China.
Yun DengSchool of Medicine, Anhui University of Science and Technology, Huainan 232001, China.
Youzhi ZhangBeijing Institute of Pharmacology and Toxicology, Beijing 100850, China.

Funding

National Natural Science Foundation of China NO. 81274117
6 · The paper itself

Abstract

Hyperthermia (HT) has broad potential for disease treatment and health maintenance. Previous studies have shown that far-infrared rays (FIRs) at 8-10 μm can potentially reduce inflammation, oxidative stress, and gut microbiota imbalance. However, the effects of FIR HT on energy metabolism require further investigation. To investigate the effects of graphene-FIR HT therapy on diet-induced obesity and their regulatory mechanisms in energy metabolism disorders. After 8 weeks of hyperthermia, mice fed standard chow or a high-fat diet (HFD) underwent body composition analysis. Energy expenditure was measured using metabolic cages. The protein changes in adipose tissue were detected by molecular technology. Graphene-FIR therapy effectively mitigated body fat accumulation, improved dyslipidemia, and impaired liver function while enhancing insulin sensitivity. Furthermore, graphene-FIR therapy increased V

Indexed as

Adipose TissueGraphiteHyperthermia, InducedInfrared RaysObesityThermogenesisUncoupling Protein 1AnimalsDiet, High-FatEnergy MetabolismMaleMiceMice, Inbred C57BLPeroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alphaGraphitePeroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alphaUcp1 protein, mouseUncoupling Protein 1adipose tissue thermogenesisAMPKgraphene-FIR therapyHFDobesity

Identifiers

PMID40076847
PMCPMC11900916

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.