Evidence map›Paper›PMID 40076772›Full record

ReviewInternational journal of molecular sciences2025

Shape Matters: The Utility and Analysis of Altered Yeast Mitochondrial Morphology in Health, Disease, and Biotechnology.

Therese Kichuk, José L Avalos

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Advances in mitochondrial compartmentalization for terpenoid synthesis inFrontiers in bioengineering and biotechnology · 2026
    Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Therese KichukDepartment of Molecular Biology, Princeton University, Princeton, NJ 08544, USA.
José L AvalosDepartment of Molecular Biology, Princeton University, Princeton, NJ 08544, USA.

Funding

The Impact of Mitochondrial Pyruvate Carriers on Metabolism and Subcellular DynamicsF30GM139398 · NIGMS · PRINCETON UNIVERSITY · PI KICHUK, THERESE · 2020 to 2022
$153k
NIGMS NIH HHS F30 GM139398
6 · The paper itself

Abstract

Mitochondria are involved in a wide array of critical cellular processes from energy production to cell death. The morphology (size and shape) of mitochondrial compartments is highly responsive to both intracellular and extracellular conditions, making these organelles highly dynamic. Nutrient levels and stressors both inside and outside the cell inform the balance of mitochondrial fission and fusion and the recycling of mitochondrial components known as mitophagy. The study of mitochondrial morphology and its implications in human disease and microbial engineering have gained significant attention over the past decade. The yeast

Indexed as

MitochondriaSaccharomyces cerevisiaeAnimalsBiotechnologyHumansMitochondrial DynamicsMitophagyanalysisbiofuelcancercontact sitesengineeringfissionfusionimagingmitochondriamorphologyneurodegenerativepathology

Identifiers

PMID40076772
PMCPMC11899761

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.