Evidence map›Paper›PMID 40076666›Full record

ArticleInternational journal of molecular sciences2025

Effects of Deoxynivalenol Detoxifier on Growth Performance, Blood Biochemical Indices, and Microbiota Composition of Piglets.

Luyao Zhang, Yongwei Wang, Weiwei Wang, Li Wang, Jingjing Shi, Junlin Cheng, Jing Zhang, Aike Li, Beibei He, Zhiyong Fan

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Luyao ZhangAcademy of National Food and Strategic Reserves Administration, Beijing 100037, China.
Yongwei WangAcademy of National Food and Strategic Reserves Administration, Beijing 100037, China.
Weiwei WangAcademy of National Food and Strategic Reserves Administration, Beijing 100037, China.
Li WangAcademy of National Food and Strategic Reserves Administration, Beijing 100037, China.
Jingjing ShiAcademy of National Food and Strategic Reserves Administration, Beijing 100037, China.
Junlin ChengAcademy of National Food and Strategic Reserves Administration, Beijing 100037, China.
Jing ZhangAcademy of National Food and Strategic Reserves Administration, Beijing 100037, China.
Aike LiAcademy of National Food and Strategic Reserves Administration, Beijing 100037, China.
Beibei HeAcademy of National Food and Strategic Reserves Administration, Beijing 100037, China.ORCID 0000-0001-9576-9493
Zhiyong FanCollege of Animal Science and Technology, Hunan Agricultural University, Changsha 410215, China.

Funding

National Key Research and Development Program of China 2021YFD1300300
6 · The paper itself

Abstract

Deoxynivalenol (DON), also known as vomitoxin, has a high detection and exceeding rate in feed and is prone to causing symptoms such as loss of appetite, weight loss, vomiting, and diarrhoea in animals, which brings great harm to the aquaculture industry. The common mycotoxin adsorbents have low adsorption rates for DON, and the use of biological methods to remove DON in feeds has gradually become a research trend. One hundred and twenty crossbred barrows were randomly divided into four groups, which included the normal diet group (CON), normal diet + detoxifier group (Det), DON-polluted diet group (DON), and DON-polluted diet + DON detoxifier group (DON + Det); the experiment lasted for 28 d. The results showed that, compared with piglets fed a normal diet, those piglets fed DON-polluted diets significantly decreased their average daily gain (ADG) and average daily feed intake (ADFI) during the 1-14 d and 1-28 d periods; the content of immunoglobulin G (IgG), catalase (CAT), superoxide dismutase (SOD), glutathione peroxidase (GSH-PX), interleukin-4 (IL-4), and interleukin-10 (IL-10) in serum was decreased; and the content of aminotransferase (AST), alanine aminotransferase (ALT), malondialdehyde (MDA), diamine oxidase (DAO), and endotoxin (LPS) was increased in pigs fed DON-polluted diets; meanwhile, feeding piglets DON-polluted diets significantly reduced the levels of acetic acid, propionic acid, and total short-chain fatty acids (SCFAs) as well as gut microbiota health index (GMHI) in piglet faeces, but increased the relative abundance of

Indexed as

Animal FeedGastrointestinal MicrobiomeTrichothecenesAnimalsGlutathione PeroxidaseMaleSwinedeoxynivalenolGlutathione PeroxidaseTrichothecenesblood biochemical indicescomposite detoxifierdeoxynivalenolgrowth performancemicrobiota compositionpiglets

Identifiers

PMID40076666
PMCPMC11900542

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.