Evidence map›Paper›PMID 40076662›Full record

ArticleInternational journal of molecular sciences2025

The Combined Assessment of CTC and

Malgorzata Szostakowska-Rodzos, Ewa A Grzybowska, Izabella Mysliwy, Renata Zub, Agnieszka Jagiello-Gruszfeld, Maryna Rubach, Aleksandra Konieczna, Anna Fabisiewicz

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Malgorzata Szostakowska-RodzosDepartment of Molecular and Translational Oncology, Maria Sklodowska-Curie National Research Institute of Oncology, Roentgena 5, 02-781 Warsaw, Poland.ORCID 0000-0002-7880-1938
Ewa A GrzybowskaDepartment of Molecular and Translational Oncology, Maria Sklodowska-Curie National Research Institute of Oncology, Roentgena 5, 02-781 Warsaw, Poland.
Izabella MysliwyDepartment of Molecular and Translational Oncology, Maria Sklodowska-Curie National Research Institute of Oncology, Roentgena 5, 02-781 Warsaw, Poland.ORCID 0000-0002-7789-3869
Renata ZubCancer Molecular and Genetic Diagnostics Department, Maria Sklodowska-Curie National Research Institute of Oncology, Roentgena 5, 02-781 Warsaw, Poland.
Agnieszka Jagiello-GruszfeldOncological Clinic, Oncological Mazovian Hospital, al. Solidarności 10, 03-411 Warsaw, Poland.ORCID 0000-0002-2698-5499
Maryna RubachCancer Chemotherapy Day Unit, Maria Sklodowska-Curie National Research Institute of Oncology, Roentgena 5, 02-781 Warsaw, Poland.
Aleksandra KoniecznaDepartment of Breast Cancer and Reconstructive Surgery, Maria Sklodowska-Curie National Research Institute of Oncology, Roentgena 5, 02-781 Warsaw, Poland.
Anna FabisiewiczDepartment of Molecular and Translational Oncology, Maria Sklodowska-Curie National Research Institute of Oncology, Roentgena 5, 02-781 Warsaw, Poland.ORCID 0000-0002-9334-1773

Funding

Narodowe Centrum Nauki 2016/21/B/NZ2/03473; 2019/33/N/NZ5/00758The Maria Sklodowska-Curie National Research Institute of Oncology SN/MGW19/2024
6 · The paper itself

Abstract

Monitoring of metastatic breast cancer (mBC) is an important issue in the clinical management of patients. Liquid biopsy has become a non-invasive method for detecting and monitoring cancer in body fluids. The presence of circulating tumor cells (CTCs) and circulating tumor DNA (ctDNA) in peripheral blood indicates poor prognosis and may contribute to early detection of progression, but assessment of these levels is still not routine clinical management. The main objective of this study was to estimate the frequency and clinical value of the

Indexed as

Breast NeoplasmsEstrogen Receptor alphaNeoplastic Cells, CirculatingAdultAgedBiomarkers, TumorCirculating Tumor DNAClass I Phosphatidylinositol 3-KinasesFemaleHumansLiquid BiopsyMiddle AgedMutationNeoplasm MetastasisPrognosisBiomarkers, TumorCirculating Tumor DNAClass I Phosphatidylinositol 3-KinasesESR1 protein, humanEstrogen Receptor alphaPIK3CA protein, humanbreast cancercirculating tumor cellscirculating tumor DNAdroplet digital PCRESR1 mutationliquid biopsyPI3K mutation

Identifiers

PMID40076662
PMCPMC11900918

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.