Evidence map›Paper›PMID 40076600›Full record

ArticleInternational journal of molecular sciences2025

Expression, Characterization and Selective Chemical Inhibition of Essential

Patrick J Skelly, Akram A Da'dara

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Patrick J SkellyMolecular Helminthology Laboratory, Department of Infectious Disease and Global Health, Cummings School of Veterinary Medicine, Tufts University, North Grafton, MA 01536, USA.
Akram A Da'daraMolecular Helminthology Laboratory, Department of Infectious Disease and Global Health, Cummings School of Veterinary Medicine, Tufts University, North Grafton, MA 01536, USA.ORCID 0000-0003-3318-9623

Funding

Tegumental acetylcholinesterase as a therapeutic target for schistosomiasisR21AI137667 · NIAID · TUFTS UNIVERSITY BOSTON · PI SKELLY, PATRICK J · 2018 to 2019
$454k
National Institutes of Health, National Institute of Allergy and Infectious Diseases AI137667NIAID NIH HHS HHSN272201000005CNIAID NIH HHS HHSN272201000005INIAID NIH HHS R21 AI137667
6 · The paper itself

Abstract

Schistosomiasis, a parasitic disease caused by worms of the genus

Indexed as

AcetylcholinesteraseCholinesterase InhibitorsHelminth ProteinsSchistosoma mansoniAnimalsHumansSchistosomiasis mansoniAcetylcholinesteraseCholinesterase InhibitorsHelminth Proteinsacetylcholinesteraseenzyme inhibitionnon-neuronalSchistosomaschistosomiasistegumenttherapy

Identifiers

PMID40076600
PMCPMC11900278

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.