Evidence map›Paper›PMID 40076569›Full record

ArticleInternational journal of molecular sciences2025

Prognostic Biomarkers in Breast Cancer via Multi-Omics Clustering Analysis.

Federica Malighetti, Matteo Villa, Alberto Maria Villa, Sara Pelucchi, Andrea Aroldi, Diego Luigi Cortinovis, Stefania Canova, Serena Capici, Marina Elena Cazzaniga, Luca Mologni and 2 more

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Federica MalighettiDepartment of Medicine and Surgery, University of Milano-Bicocca, 20900 Monza, Italy.ORCID 0009-0009-2492-8974
Matteo VillaDepartment of Medicine and Surgery, University of Milano-Bicocca, 20900 Monza, Italy.ORCID 0000-0002-6534-642X
Alberto Maria VillaDepartment of Medicine and Surgery, University of Milano-Bicocca, 20900 Monza, Italy.ORCID 0009-0008-7757-7365
Sara PelucchiDepartment of Medicine and Surgery, University of Milano-Bicocca, 20900 Monza, Italy.ORCID 0000-0002-9902-9641
Andrea AroldiDepartment of Medicine and Surgery, University of Milano-Bicocca, 20900 Monza, Italy.ORCID 0000-0002-3428-5353
Diego Luigi CortinovisDepartment of Medicine and Surgery, University of Milano-Bicocca, 20900 Monza, Italy.ORCID 0000-0001-7611-7369
Stefania CanovaOncology Unit, Fondazione IRCCS San Gerardo dei Tintori, 20900 Monza, Italy.ORCID 0009-0006-4251-8889
Serena CapiciPhase 1 Unit, Fondazione IRCCS San Gerardo dei Tintori, 20900 Monza, Italy.
Marina Elena CazzanigaDepartment of Medicine and Surgery, University of Milano-Bicocca, 20900 Monza, Italy.
Luca MologniDepartment of Medicine and Surgery, University of Milano-Bicocca, 20900 Monza, Italy.ORCID 0000-0002-6365-5149
Daniele RamazzottiDepartment of Medicine and Surgery, University of Milano-Bicocca, 20900 Monza, Italy.ORCID 0000-0002-6087-2666
Nicoletta CordaniDepartment of Medicine and Surgery, University of Milano-Bicocca, 20900 Monza, Italy.ORCID 0000-0002-3227-8280

Funding

Italian Association for Cancer Research IG24828
6 · The paper itself

Abstract

Breast cancer (BC) is a highly heterogeneous disease with diverse molecular subtypes, which complicates prognosis and treatment. In this study, we performed a multi-omics clustering analysis using the Cancer Integration via MultIkernel LeaRning (CIMLR) method on a large BC dataset from The Cancer Genome Atlas (TCGA) to identify key prognostic biomarkers. We identified three genes-

Indexed as

Antigens, NeoplasmBiomarkers, TumorBreast NeoplasmsLIM Domain ProteinsCell Line, TumorCluster AnalysisDrug Resistance, NeoplasmFemaleGene Expression ProfilingGene Expression Regulation, NeoplasticHumansMultiomicsPrognosisAntigens, NeoplasmBiomarkers, TumorLIM Domain ProteinsPRAME protein, humanbreast cancermulti-omics landscapeprognostic biomarkers

Identifiers

PMID40076569
PMCPMC11900291

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.