Evidence map›Paper›PMID 40076499›Full record

ArticleInternational journal of molecular sciences2025

Novel Triazeneindole Antibiotics: Synthesis and Hit-to-Lead Optimization.

Boris Sorokin, Alla Filimonova, Anna Emelianova, Vadim Kublitski, Artem Gvozd, Vladimir Shmygarev, Ilia Yampolsky, Elena Guglya, Evgeniy Gusev, Denis Kuzmin

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Boris SorokinMoscow Center for Advanced Studies, Kulakova Str. 20, 123592 Moscow, Russia.ORCID 0009-0009-2773-3486
Alla FilimonovaKurchatov Centre for Genome Research, National Research Centre "Kurchatov Institute", 123182 Moscow, Russia.
Anna EmelianovaMoscow Center for Advanced Studies, Kulakova Str. 20, 123592 Moscow, Russia.
Vadim KublitskiShemyakin and Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 117997 Moscow, Russia.ORCID 0000-0001-7142-2794
Artem GvozdShemyakin and Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 117997 Moscow, Russia.
Vladimir ShmygarevShemyakin and Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 117997 Moscow, Russia.
Ilia YampolskyShemyakin and Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 117997 Moscow, Russia.
Elena GuglyaShemyakin and Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 117997 Moscow, Russia.ORCID 0000-0003-2433-8201
Evgeniy GusevSevertsov Institute of Ecology and Evolution, Russian Academy of Sciences, Leninsky Prospect 33, 119071 Moscow, Russia.
Denis KuzminMoscow Center for Advanced Studies, Kulakova Str. 20, 123592 Moscow, Russia.

Funding

Ministry of Science and Higher Education of the Russian Federation FSMG-2021-0006, "Digital technologies for solving problems of quantitative medicine", agree-ment 075-03-2024-117 dated 17 January 2024
6 · The paper itself

Abstract

Bacterial antibiotic resistance represents a major healthcare problem. In 2019, 4.95 million deaths were associated with antibiotic resistance, and it is estimated that, by 2050, up to 3.8% of the global gross domestic product could be lost due to this problem. Methicillin-resistant

Indexed as

Anti-Bacterial AgentsIndolesMethicillin-Resistant Staphylococcus aureusAnimalsDrug Resistance, Multiple, BacterialHumansMaleMicrobial Sensitivity TestsRatsStaphylococcal InfectionsAnti-Bacterial AgentsIndolesABSSSIADME-Toxantibiotichit-to-leadMRSAtriazeneindole

Identifiers

PMID40076499
PMCPMC11899342

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.