Evidence map›Paper›PMID 40076494›Full record

ArticleInternational journal of molecular sciences2025

CYP4X1 Expression Is Associated with Metastasis and Poor Prognosis in Patients with Colorectal Cancer.

Sooyoun Kim, Hakchun Kim, Inpyo Hong, Minho Lee, Hyeongjoo Kim, Hyoungjong Kwak, Chang-Jin Kim, Donghyun Kang, Taesung Ahn, Moojun Baek and 1 more

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Sooyoun KimDepartment of Pathology, College of Medicine, Soonchunhyang University, 31 Soonchunhyang 6-gil, Dongnam-gu, Cheonan 31151, Chungcheongnam-do, Republic of Korea.
Hakchun KimSoonchunhyang Medical Science Research Institute, College of Medicine, Soonchunhyang University, 25 Bongjeong-ro, Dongnam-gu, Cheonan 31151, Chungcheongnam-do, Republic of Korea.
Inpyo HongDepartment of Pathology, College of Medicine, Soonchunhyang University, 31 Soonchunhyang 6-gil, Dongnam-gu, Cheonan 31151, Chungcheongnam-do, Republic of Korea.
Minho LeeDepartment of Pathology, College of Medicine, Soonchunhyang University, 31 Soonchunhyang 6-gil, Dongnam-gu, Cheonan 31151, Chungcheongnam-do, Republic of Korea.
Hyeongjoo KimR&D Center Pharmaceutical Laboratory, Korean Drug Co., Ltd., 34, Nonhyeon-ro 28-gil, Gangnam-gu, Seoul 06300, Republic of Korea.
Hyoungjong KwakResearch Institute of Clinical Medicine, Woori Madi Medical Center, 111 Baekjedae-ro, Wansan-gu, Jeonju 55082, Jeollabuk-do, Republic of Korea.
Chang-Jin KimResearch Institute of Clinical Medicine, Woori Madi Medical Center, 111 Baekjedae-ro, Wansan-gu, Jeonju 55082, Jeollabuk-do, Republic of Korea.
Donghyun KangDepartment of Surgery, College of Medicine, Soonchunhyang University, 31 Soonchunhyang 6-gil, Dongnam-gu, Cheonan 31151, Chungcheongnam-do, Republic of Korea.
Taesung AhnDepartment of Surgery, College of Medicine, Soonchunhyang University, 31 Soonchunhyang 6-gil, Dongnam-gu, Cheonan 31151, Chungcheongnam-do, Republic of Korea.ORCID 0000-0001-5617-0365
Moojun BaekDepartment of Surgery, College of Medicine, Soonchunhyang University, 31 Soonchunhyang 6-gil, Dongnam-gu, Cheonan 31151, Chungcheongnam-do, Republic of Korea.
Dongjun JeongDepartment of Pathology, College of Medicine, Soonchunhyang University, 31 Soonchunhyang 6-gil, Dongnam-gu, Cheonan 31151, Chungcheongnam-do, Republic of Korea.ORCID 0000-0001-8180-5668

Funding

The Basic Science Research Program through the National Research Foundation of Korea is funded by the Ministry of Education NRF-2021R1A6A1A03039503the Ministry of Education of the Republic of Korea and the National Research Foundation of Korea NRF-2022R1A2C2010445the Regional Innovation Mega Project program through the Korea Innovation Foundation 2023-DD-UP-0007
6 · The paper itself

Abstract

Globally, the mortality rate of colorectal cancer (CRC) remains high. Despite the development of various treatments, such as targeted therapy and immunotherapy, colorectal cancer continues to be a serious health issue worldwide. Identifying new biomarkers is essential for improving prognosis and tailoring targeted therapies for CRC. This study aims to elucidate the role of

Indexed as

Colorectal NeoplasmsCytochrome P450 Family 4Gene Expression Regulation, NeoplasticAgedAnimalsBiomarkers, TumorCell Line, TumorCell MovementCell ProliferationFemaleHumansLymphatic MetastasisMaleMiceMiddle AgedNeoplasm MetastasisBiomarkers, TumorCytochrome P450 Family 4biomarkercolorectal cancerCYP4X1prognostic markertherapeutic target

Identifiers

PMID40076494
PMCPMC11899201

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.