Evidence map›Paper›PMID 40076404›Full record

ArticleMolecules (Basel, Switzerland)2025

Performance and Mechanism of Hydrolyzed Keratin for Hair Photoaging Prevention.

Jiayi Fan, Lei Wu, Jing Wang, Xiaoying Bian, Chongchong Chen, Kuan Chang

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jiayi FanKey Laboratory of Synthetic and Biological Colloids, Ministry of Education, School of Chemical & Material Engineering, Jiangnan University, Wuxi 214122, China.
Lei WuKey Laboratory of Synthetic and Biological Colloids, Ministry of Education, School of Chemical & Material Engineering, Jiangnan University, Wuxi 214122, China.
Jing WangKey Laboratory of Synthetic and Biological Colloids, Ministry of Education, School of Chemical & Material Engineering, Jiangnan University, Wuxi 214122, China.
Xiaoying BianUnilever (China) Investing Co., Ltd., Shanghai 200335, China.
Chongchong ChenUnilever (China) Investing Co., Ltd., Shanghai 200335, China.
Kuan ChangKey Laboratory of Synthetic and Biological Colloids, Ministry of Education, School of Chemical & Material Engineering, Jiangnan University, Wuxi 214122, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Photoaging is common and represents one of the primary pathways for hair damage in daily life. Hydrolyzed keratin, which is usually derived from wool and consists of a series of polypeptide molecules, has been investigated as a UV damage prevention ingredient for hair care. Scanning Electron Microscopy (SEM) and fluorescent penetration experiments verified that hydrolyzed keratin can deposit on the hair cuticles to form a film and partly penetrate into the hair cortex. This film played as a UV reducer and helped hair resist surface damage and maintain a sleek and healthy morphology after UV radiation. Surprisingly, it was found that hydrolyzed keratin treatment combined with subsequent UV radiation could significantly improve the tensile properties of hair. For hydrolyzed-keratin-treated hair, tensile strength was maintained after UV radiation, while, as a comparison, it decreased by 14.32% for untreated hair. This phenomenon is explained by a UV-induced degradation-penetration mechanism. During UV radiation, an increase in free amino acid content and conductivity was observed for the hydrolyzed keratin solution, demonstrating photodegradation into smaller peptides and amino acids. The degradation of hydrolyzed keratin allowed it to more easily enter the interior of the hair cortex, thereby enhancing its tensile properties by enhancing the chemical bonds.

Indexed as

HairKeratinsHumansHydrolysisMicroscopy, Electron, ScanningTensile StrengthUltraviolet RaysKeratinshair photoaginghydrolyzed keratinUV damage

Identifiers

PMID40076404
PMCPMC11902160

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.