Evidence map›Paper›PMID 40076378›Full record

ArticleMolecules (Basel, Switzerland)2025

Exploring the Inhibitory Potential of Sodium Alginate Against Digestive Enzymes Linked to Obesity and Type 2 Diabetes.

Chantal D Daub, Arryn L Michaels, Blessing Mabate, Lithalethu Mkabayi, Adrienne L Edkins, Brett I Pletschke

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Chantal D DaubEnzyme Science Programme (ESP), Department of Biochemistry, Microbiology and Bioinformatics, Rhodes University, Makhanda 6139, South Africa.ORCID 0000-0001-7914-6229
Arryn L MichaelsEnzyme Science Programme (ESP), Department of Biochemistry, Microbiology and Bioinformatics, Rhodes University, Makhanda 6139, South Africa.ORCID 0000-0003-1875-0187
Blessing MabateEnzyme Science Programme (ESP), Department of Biochemistry, Microbiology and Bioinformatics, Rhodes University, Makhanda 6139, South Africa.ORCID 0000-0002-3584-5703
Lithalethu MkabayiEnzyme Science Programme (ESP), Department of Biochemistry, Microbiology and Bioinformatics, Rhodes University, Makhanda 6139, South Africa.ORCID 0000-0001-7620-5596
Adrienne L EdkinsBiomedical Biotechnology Research Unit (BioBRU), Department of Biochemistry, Microbiology and Bioinformatics, Rhodes University, Makhanda 6139, South Africa.ORCID 0000-0002-3615-6651
Brett I PletschkeEnzyme Science Programme (ESP), Department of Biochemistry, Microbiology and Bioinformatics, Rhodes University, Makhanda 6139, South Africa.ORCID 0000-0001-8117-1730

Funding

Department of Science and Innovation Industrial Biocatalysis Hub (IBH)German Academic Exchange Service 57408782National Research Foundation 98566 and 105829Pearson-Young Memorial fellowshipRhodes University RRRG- Pletschke
6 · The paper itself

Abstract

Obesity and type 2 diabetes mellitus (T2DM) are major health concerns worldwide, often managed with treatments that have significant limitations and side effects. This study examines the potential of sodium alginates, extracted from

Indexed as

AlginatesDiabetes Mellitus, Type 2Enzyme InhibitorsObesityalpha-Amylasesalpha-GlucosidasesGlucoseGlycoside Hydrolase InhibitorsHumansLipaseSucraseAlginatesalpha-Amylasesalpha-GlucosidasesEnzyme InhibitorsGlucoseGlycoside Hydrolase InhibitorsLipaseSucrasedigestive enzyme inhibitionobesitysodium alginatetype 2 diabetes mellitus

Identifiers

PMID40076378
PMCPMC11902270

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.