Evidence map›Paper›PMID 40076344›Full record

ArticleMolecules (Basel, Switzerland)2025

Highly Sensitive Temperature Sensing in Biological Region with Ratiometric Fluorescent Response.

Yan Li, Han Yu, Hongjuan Li, Shiguo Sun, Ruijin Yu, Yongqian Xu

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yan LiCollege of Chemistry & Pharmacy, Northwest A&F University, Yangling 712100, China.
Han YuCollege of Chemistry & Pharmacy, Northwest A&F University, Yangling 712100, China.ORCID 0009-0000-8109-1693
Hongjuan LiCollege of Chemistry & Pharmacy, Northwest A&F University, Yangling 712100, China.ORCID 0000-0003-4088-7083
Shiguo SunCollege of Chemistry & Pharmacy, Northwest A&F University, Yangling 712100, China.
Ruijin YuCollege of Chemistry & Pharmacy, Northwest A&F University, Yangling 712100, China.
Yongqian XuCollege of Chemistry & Pharmacy, Northwest A&F University, Yangling 712100, China.ORCID 0000-0002-3778-7332

Funding

National Natural Science Foundation of China 21978241Science Foundation of Shaanxi Province 2023-YBSF-224
6 · The paper itself

Abstract

Poly(2-oxazoline) (POx), a typical thermoresponsive polymer with good biocompatibility, was conjugated with environment-sensitive tetraphenylenethene (TPE) and hydroxyphenylbenzoxazole (HBO) to achieve unique thermometer readings. Through phase transition induced by temperature, the thermometers can measure temperature in biologic range with ratiometric fluorescence response, ultrahigh sensitivity and good reversibility. Moreover, the thermometer can be used to measure the change in temperature with large fluorescence difference in living cells.

Indexed as

Fluorescent DyesOxazolesPolymersTemperatureBenzoxazolesFluorescenceHumansThermometersBenzoxazolesFluorescent DyesOxazolesPolymersPoly(2-oxazoline)ratiometric fluorescencetemperature sensors

Identifiers

PMID40076344
PMCPMC11902262

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.