Evidence map›Paper›PMID 40076335›Full record

ReviewMolecules (Basel, Switzerland)2025

Recent Updates on Terpenoids and Other Bioactive Constituents of Marine Sponges.

Maggie J F Raymond, Harinantenaina L Rakotondraibe

Abstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Maggie J F RaymondDivision of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, The Ohio State University, Columbus, OH 43210, USA.
Harinantenaina L RakotondraibeDivision of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, The Ohio State University, Columbus, OH 43210, USA.ORCID 0000-0003-2166-4992

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Marine sponges are a promising source of bioactive secondary metabolites, contributing hundreds of novel compounds per year to natural product research, each with diverse chemical and biological properties. We have chosen to highlight marine natural products that exhibited unique structural features and/or significant bioactivity. The most common report of pharmacological significance was cytotoxicity, with antimicrobial and enzyme inhibition activities following, and mentions of other attributes, such as anti-inflammation, neuroprotection, and anti-biofilm. This review describes newly isolated constituents from sponges between 2020 and 2023 alongside their relevant pharmacological activity. The isolation, structures, and biological properties of 218 unique secondary metabolites from various chemical families, including terpenoids, peptides, and alkaloids from marine sponges, are covered.

Indexed as

Biological ProductsPoriferaTerpenesAlkaloidsAnimalsAnti-Infective AgentsAnti-Inflammatory AgentsAquatic OrganismsHumansAlkaloidsAnti-Infective AgentsAnti-Inflammatory AgentsBiological ProductsTerpenesalkaloidbioactivitymarine spongenatural productpeptideterpenoid

Identifiers

PMID40076335
PMCPMC11901466

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.