Synthesis of Enantiostructured Triacylglycerol Prodrugs Constituting an Active Drug Located at Terminal

Lena Rós Jónsdottir, Gudmundur G Haraldsson

Abstract read

In one paragraph

Article in Molecules (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it

0cells of the map it votes in

1citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

Stigmasterol-Acylglycerol Conjugates: Chemoenzymatic Synthesis as a Shorter Alternative to Chemical Routes and the Impact of Fatty Acid Chain Length on the Physicochemical Parameters of Liposomes.Molecules (Basel, Switzerland) · 2026
Article

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Lena Rós JónsdottirScience Institute, Chemistry Department, University of Iceland, Dunhaga 3, 107 Reykjavik, Iceland.

Gudmundur G HaraldssonScience Institute, Chemistry Department, University of Iceland, Dunhaga 3, 107 Reykjavik, Iceland.ORCID 0000-0002-5664-2745

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The current paper reports the asymmetric synthesis of a focused library of enantiostructured triacylglycerols (TAGs) constituting a potent drug of the NSAID type (ibuprofen or naproxen) along with a pure bioactive n-3 polyunsaturated fatty acid (PUFA) intended as a novel type of prodrug. In this second category, a TAG prodrug of the terminal

Indexed as

GlycerolProdrugsTriglyceridesFatty Acids, Omega-3Fungal ProteinsIbuprofenLipaseMolecular StructureNaproxenStereoisomerismFatty Acids, Omega-3Fungal ProteinsGlycerolIbuprofenLipaselipase B, Candida antarcticaNaproxenProdrugsTriglyceridesacylglycerol prodrugsasymmetric synthesisenantiostructured triacylglycerolslipasen-3 PUFAs(S)-ibuprofen(S)-naproxen

Identifiers

PMID40076218

DOI10.3390/molecules30050991

PMCPMC11902219

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.