Evidence map›Paper›PMID 40075967›Full record

ArticleAnimals : an open access journal from MDPI2025

The Gut Microbiota of the Greater Horseshoe Bat Confers Rapidly Corresponding Immune Cells in Mice.

Shan Luo, Xinlei Huang, Siyu Chen, Junyi Li, Hui Wu, Yuhua He, Lei Zhou, Boyu Liu, Jiang Feng

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Animals : an open access journal from MDPI, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Shan LuoCollege of Animal Science and Technology, Jilin Agricultural Science and Technology University, Jilin 132109, China.
Xinlei HuangCollege of Life Science, Jilin Agricultural University, Changchun 130117, China.
Siyu ChenCollege of Animal Science and Technology, Jilin Agricultural Science and Technology University, Jilin 132109, China.
Junyi LiCollege of Veterinary Medicine, Jilin Agricultural University, Changchun 130117, China.
Hui WuCollege of Life Science, Jilin Agricultural University, Changchun 130117, China.
Yuhua HeCollege of Animal Science and Technology, Jilin Agricultural Science and Technology University, Jilin 132109, China.
Lei ZhouCollege of Animal Science and Technology, Jilin Agricultural Science and Technology University, Jilin 132109, China.
Boyu LiuCollege of Animal Science and Technology, Jilin Agricultural Science and Technology University, Jilin 132109, China.ORCID 0000-0001-5645-005X
Jiang FengCollege of Life Science, Jilin Agricultural University, Changchun 130117, China.

Funding

College Students' Innovative Entrepreneurial Training Plan Program 202311439011
6 · The paper itself

Abstract

backgroundEmerging infectious diseases threaten human and animal health, with most pathogens originating from wildlife. Bats are natural hosts for many infectious agents. Previous studies have demonstrated that changes in some specific genes in bats may contribute to resistance to viral infections, but they have mostly overlooked the immune function of the bat gut microbiota.

aimsIn this study, we used fecal transplants to transfer the gut microbiota from the Greater Horseshoe Bat (

resultsThe results showed that the gut microbiota of mice showed characteristics of some bat gut microbiota. The Greater Horseshoe Bat's gut microbiota changed some immune cells' composition in the spleen and mesenteric lymph nodes of mice and also conferred a faster and higher proportion of natural killer cell activation.

conclusionThis result provides new evidence for the regulatory immune function of bat gut microbiota and contributes to a deeper insight into the unique immune system of bats.

Indexed as

batsChiropterafecal transplantimmunomodulationmicrobiota

Identifiers

PMID40075967
PMCPMC11899282

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.