ArticleAnimals : an open access journal from MDPI2025
Dietary Pea Fibre Improves Obesity, Intestinal Barrier, Reproductive Performance, Offspring Health of Parent Mice Deprived of Dietary Fibre.
Article in Animals : an open access journal from MDPI, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Dietary Interventions Targeting Maternal Obesity: Intergenerational Effects, Mechanisms, and Translational Insights.Current nutrition reports · 2026Review
- Dietary pulse prebiotic fibre intake in a rat obese pregnancy model alters maternal caecal microbiome and protects against steatosis in newly weaned offspring.Journal of nutritional science · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
Abstract
As a potential high-quality protein food, peas are enriched in protein and fibre. This study investigated the judicious utilisation of pea fibre and the impact of maternal diet on offspring health in mice. Thirty-six eight-week-old, female, healthy C57BL/6J mice were divided into three groups at random (n = 12 per group): deprived fibre diet (DFD), 5% pea fibre diet (LFD), and 10% pea fibre diet (HFD). After weaning, the offspring mice were fed the same diet as their parents; the respective corresponding groups were DFDO, LFDO, and HFDO. Fibre-deprived mice exhibited decreased average litter size, diminished reproductive performance, increased body weight, and intestinal barrier damage. Mice fed pea fibre showed increased litter size, improved fertility rate of parental mice, regulated body weight, and maintained a normal intestinal barrier morphology without inflammatory cell infiltration. Furthermore, 16S rRNA analysis revealed that pea fibre enhanced diversity and richness of the intestinal microbiota and altered microbial composition. Notably, changes in
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.