Evidence map›Paper›PMID 40075934›Full record

ReviewAnimals : an open access journal from MDPI2025

Gut Metabolome in Companion Animal Nutrition-Linking Diets to Health.

Yang Lyu, Junning Pu, Baichuan Deng, Caimei Wu

Abstract readReview
In one paragraph

Review in Animals : an open access journal from MDPI, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
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  7. Article
  8. Effect of yeast probioticFrontiers in microbiology · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Yang LyuKey Laboratory of Animal Disease-Resistance Nutrition, Sichuan Province, Ministry of Agriculture and Rural Affairs, Ministry of Education, Animal Nutrition Institute, Sichuan Agricultural University, Chengdu 611130, China.ORCID 0000-0002-6009-303X
Junning PuKey Laboratory of Animal Disease-Resistance Nutrition, Sichuan Province, Ministry of Agriculture and Rural Affairs, Ministry of Education, Animal Nutrition Institute, Sichuan Agricultural University, Chengdu 611130, China.
Baichuan DengGuangdong Provincial Key Laboratory of Animal Nutrition Control, College of Animal Science, South China Agricultural University, Guangzhou 510642, China.ORCID 0000-0002-0713-1463
Caimei WuKey Laboratory of Animal Disease-Resistance Nutrition, Sichuan Province, Ministry of Agriculture and Rural Affairs, Ministry of Education, Animal Nutrition Institute, Sichuan Agricultural University, Chengdu 611130, China.ORCID 0000-0001-8437-0073

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tailoring diet to support a healthy gut microbiome is key for animal well-being. The gut metabolome, including all small molecules in the gut, is central to diet-microbiome-health interactions. While comprehension of the gut metabolome in companion animal nutrition is emerging, a substantial number of studies have been undertaken to elucidate the metabolomic shifts and identify specific marker metabolites influenced by diverse dietary interventions. By employing various metabolomic approaches, researchers have extensively documented the effects of different diet types, nutrient compositions, and dietary supplements on the gut metabolome in dogs and cats. Despite these advancements, there remains several notable limitations, including a lack of integrated microbiome analysis, incomplete understanding of specific marker metabolites, and an over-reliance on extrapolating findings from human studies. Therefore, this review aims to summarize the current understanding of the canine and feline gut metabolome, while exploring future possibilities and challenges for the field.

Indexed as

catsdogsgut healthmetabolomicspet food

Identifiers

PMID40075934
PMCPMC11898145

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.