Evidence map›Paper›PMID 40075913›Full record

ArticleAnimals : an open access journal from MDPI2025

Growth Parameters and Growth-Related Hormone Profile in a Herd of Cattle up to 4 Years of Age Derived from Assisted Reproductive Technologies.

Sonia Heras, Jordana Sena Lopes, Armando Quintero-Moreno, Jon Romero-Aguirregomezcorta, Sebastian Canovas, Raquel Romar, Pilar Coy

Abstract read
In one paragraph

Article in Animals : an open access journal from MDPI, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Sonia HerasPhysiology of Reproduction Group, Department of Physiology, IMIB-Pascual Parrilla, University of Murcia, 30100 Murcia, Spain.ORCID 0000-0001-7784-965X
Jordana Sena LopesPhysiology of Reproduction Group, Department of Physiology, IMIB-Pascual Parrilla, University of Murcia, 30100 Murcia, Spain.ORCID 0000-0002-8419-7845
Armando Quintero-MorenoPhysiology of Reproduction Group, Department of Physiology, IMIB-Pascual Parrilla, University of Murcia, 30100 Murcia, Spain.
Jon Romero-AguirregomezcortaPhysiology of Reproduction Group, Department of Physiology, IMIB-Pascual Parrilla, University of Murcia, 30100 Murcia, Spain.ORCID 0000-0001-7779-6869
Sebastian CanovasPhysiology of Reproduction Group, Department of Physiology, IMIB-Pascual Parrilla, University of Murcia, 30100 Murcia, Spain.ORCID 0000-0003-4190-6258
Raquel RomarPhysiology of Reproduction Group, Department of Physiology, IMIB-Pascual Parrilla, University of Murcia, 30100 Murcia, Spain.ORCID 0000-0003-0492-289X
Pilar CoyPhysiology of Reproduction Group, Department of Physiology, IMIB-Pascual Parrilla, University of Murcia, 30100 Murcia, Spain.ORCID 0000-0002-3943-1890

Funding

Ministerio de ciencia e innovación CO-MZ-14Ministerio de ciencia e innovación IJC2019-039404-IMinisterio de Ciencia e innovación PID2020-113366RB-I00
6 · The paper itself

Abstract

Assisted reproductive technologies (ART) are routinely used in livestock to generate animals of high genetic value. Despite representing an outstanding accomplishment, recent studies suggest differences in health, fertility, and gestational length of in vitro-produced compared to in vivo-derived animals. Currently, there are no data available on the long-term effects of ART on growth and development. This observational study aimed to understand the relationship between growth and growth-influencing hormones in a herd of cattle derived from artificial insemination (AI) or from in vitro-produced embryos either with BSA (C-IVP) or with reproductive fluids (RF-IVP) as a protein source in culture. Cortisol was associated positively with weight in AI and negatively with body length in males. Thyroxine decreased with age, and it was positively associated with thoracic circumference in RF-IVP. Insulin-like growth factor-1 was greater in RF-IVP than in C-IVP, and it was positively associated with body length and withers height. Growth hormone was greater in females than in males and RF-IVP compared to AI and C-IVP. In conclusion, we present here the first datasets on growth parameters and growth-influencing hormones in cattle from birth to 4 years of age without observing major evidence of differences depending on the embryo origin.

Indexed as

animal healthassisted reproductive technologiescattlegrowth parametersgrowth-related hormoneslong-term impact

Identifiers

PMID40075913
PMCPMC11898124

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.