Evidence map›Paper›PMID 40075732›Full record

ReviewCancers2025

Diffuse Large B-Cell Lymphoma in the Older and Frail Patient.

Emily C Ayers, Sonali M Smith

Abstract readReview
In one paragraph

Review in Cancers, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Emily C AyersDivision of Hematology and Oncology, University of Virginia School of Medicine, Charlottesville, VA 22903, USA.ORCID 0000-0003-3748-4507
Sonali M SmithSection of Hematology/Oncology, Department of Medicine, University of Chicago, Chicago, IL 60637, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Outcomes in older, unfit, and frail patients with diffuse large B-cell lymphoma (DLBCL) are inferior compared to younger and fit patients. Despite tremendous progress in the treatment landscape of DLBCL, few clinical trials have focused specifically on this high-risk patient population. This review focuses on the pathophysiology unique to the older patient with DLBCL, as well as the evidence behind current treatment approaches. This article also aims to highlight emerging prognostic tools and novel treatment strategies that may improve the outcomes in this patient cohort in the future.

Indexed as

diffuse large B-cell lymphomafrailty assessmentgeriatric assessmentolder adults

Identifiers

PMID40075732
PMCPMC11899176

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.