Evidence map›Paper›PMID 40075687›Full record

ArticleCancers2025

The Role of Engagement in Virtual Reality to Enhance Emotional Well-Being in Breast Cancer Patients: A Mediation Analysis.

Hélène Buche, Aude Michel, Royce Anders, Nathalie Blanc

Abstract read
In one paragraph

Article in Cancers, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. The influence of virtual reality on anxiety and pain in breast cancer patients: A systematic review.Technical innovations & patient support in radiation oncology · 2026
    Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Hélène BucheLaboratoire Epsylon EA 4556, Université Paul Valéry, 34090 Montpellier, France.ORCID 0009-0005-2176-4418
Aude MichelLaboratoire Epsylon EA 4556, Université Paul Valéry, 34090 Montpellier, France.ORCID 0009-0008-1263-1922
Royce AndersLaboratoire Epsylon EA 4556, Université Paul Valéry, 34090 Montpellier, France.ORCID 0000-0002-9745-3385
Nathalie BlancLaboratoire Epsylon EA 4556, Université Paul Valéry, 34090 Montpellier, France.ORCID 0000-0003-1327-0280

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionVirtual reality (VR) has garnered increasing attention in oncology due to its potential to enhance patient care by alleviating anxiety and emotional distress. The present work evaluates the hypothesis proposed by a recent theoretical model that engagement and the sense of presence are key mediators that impact the degree of beneficial effects that VR may have on the emotional well-being of breast cancer patients.

methodsThis study draws on data from three previous studies comprising 156 breast cancer patients. The psychological variables of well-being studied included emotional dimensions measured before and after exposure to a virtual environment, as well as factors related to immersive qualities. Correlation and mediation analyses were conducted to explore relationships among said variables, namely, one's tendency to be immersed in an activity, engagement, spatial presence, and emotional well-being (i.e., valence and arousal) of the patients.

resultsEngagement plays a crucial mediating role between tendency of immersion, spatial presence, and positive emotional responses. Patients with a greater tendency toward immersion and higher engagement in the virtual environment showed significant emotional improvements. However, tendency of immersion and spatial presence alone did not directly lead to more positive emotional experiences; their influence was primarily exerted through engagement.

conclusionsEngagement emerges as a fundamental lever for maximizing the psychological benefits of VR in oncology. Clinical interventions using VR should prioritize optimizing engagement in immersive environments to improve patients' emotional state throughout their cancer treatment journey.

Indexed as

breast canceremotional well-beingengagementimmersionsense of presencevirtual reality

Identifiers

PMID40075687
PMCPMC11899700

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.