Evidence map›Paper›PMID 40075658›Full record

ArticleCancers2025

A Novel Digital PCR Assay for Accurate Detection and Differentiation of Focal and Non-Focal Subtypes of Mesenchymal-Epithelial Transition (

Raymond C M Shek, Peggy S N Li, Shelley C M Leung, H T Chu, F Hioe, Victor W L Tang, Y H Lui, Larry R S Lam, Joshua H Y Ng, Raiden T S Wong and 3 more

Abstract read
In one paragraph

Article in Cancers, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Raymond C M ShekDepartment of Pathology, Pamela Youde Nethersole Eastern Hospital, Hospital Authority, Hong Kong, China.ORCID 0009-0008-9890-5567
Peggy S N LiDepartment of Pathology, Pamela Youde Nethersole Eastern Hospital, Hospital Authority, Hong Kong, China.
Shelley C M LeungDepartment of Pathology, Pamela Youde Nethersole Eastern Hospital, Hospital Authority, Hong Kong, China.
H T ChuDepartment of Pathology, Pamela Youde Nethersole Eastern Hospital, Hospital Authority, Hong Kong, China.ORCID 0009-0001-0189-1031
F HioeDepartment of Pathology, Pamela Youde Nethersole Eastern Hospital, Hospital Authority, Hong Kong, China.
Victor W L TangDepartment of Pathology, Pamela Youde Nethersole Eastern Hospital, Hospital Authority, Hong Kong, China.ORCID 0000-0003-2792-0248
Y H LuiDepartment of Pathology, Pamela Youde Nethersole Eastern Hospital, Hospital Authority, Hong Kong, China.
Larry R S LamDepartment of Pathology, Pamela Youde Nethersole Eastern Hospital, Hospital Authority, Hong Kong, China.
Joshua H Y NgDepartment of Pathology, Pamela Youde Nethersole Eastern Hospital, Hospital Authority, Hong Kong, China.ORCID 0000-0002-6909-8662
Raiden T S WongDepartment of Pathology, Pamela Youde Nethersole Eastern Hospital, Hospital Authority, Hong Kong, China.ORCID 0000-0002-0911-718X
Miranda C Y YauDepartment of Pathology, Pamela Youde Nethersole Eastern Hospital, Hospital Authority, Hong Kong, China.ORCID 0009-0004-3211-2020
Jimmy Y W LamDepartment of Pathology, Pamela Youde Nethersole Eastern Hospital, Hospital Authority, Hong Kong, China.
Gilman K H SiuDepartment of Health Technology and Informatics, The Hong Kong Polytechnic University, Hong Kong, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

objectivesMesenchymal-epithelial transition (

methodsThis study introduces a novel digital PCR (dPCR) assay designed not only to detect

conclusionsThis study highlights the potential of the dPCR assay to complement existing molecular diagnostic techniques, delivering reliable and actionable results for

Indexed as

digital PCRFISHfocal MET amplificationlung cancerMET amplificationMET polysomyNGS

Identifiers

PMID40075658
PMCPMC11898889

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.