Evidence map›Paper›PMID 40075625›Full record

ReviewCancers2025

Expanding Indications in Transplant Oncology.

Erlind Allkushi, Chase J Wehrle, JaeKeun Kim, Mazhar Khalil, David C H Kwon, Masato Fujiki, Antonio D Pinna, Charles Miller, Andrea Schlegel, Federico Aucejo and 2 more

Abstract readReview
In one paragraph

Review in Cancers, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Review
  3. [Research progress on liver transplantation therapy for hepatic metastases in gastroenteropancreatic neuroendocrine tumors].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2026
    Review
  4. Present and future of liver transplantation for cholangiocellular carcinoma: moving toward personalized multiparametric transplantability patterns.Transplant international : official journal of the European Society for Organ Transplantation · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Erlind AllkushiTransplantation Center, Department of Liver Transplantation, Cleveland Clinic, Cleveland, OH 44195, USA.
Chase J WehrleTransplantation Center, Department of Liver Transplantation, Cleveland Clinic, Cleveland, OH 44195, USA.ORCID 0000-0002-9275-4744
JaeKeun KimTransplantation Center, Department of Liver Transplantation, Cleveland Clinic, Cleveland, OH 44195, USA.ORCID 0000-0003-0767-6655
Mazhar KhalilTransplantation Center, Department of Liver Transplantation, Cleveland Clinic, Cleveland, OH 44195, USA.
David C H KwonTransplantation Center, Department of Liver Transplantation, Cleveland Clinic, Cleveland, OH 44195, USA.
Masato FujikiTransplantation Center, Department of Liver Transplantation, Cleveland Clinic, Cleveland, OH 44195, USA.ORCID 0000-0002-1118-0081
Antonio D PinnaTransplantation Center, Department of Liver Transplantation, Cleveland Clinic, Cleveland, OH 44195, USA.ORCID 0000-0001-6523-3858
Charles MillerTransplantation Center, Department of Liver Transplantation, Cleveland Clinic, Cleveland, OH 44195, USA.
Andrea SchlegelTransplantation Center, Department of Liver Transplantation, Cleveland Clinic, Cleveland, OH 44195, USA.
Federico AucejoTransplantation Center, Department of Liver Transplantation, Cleveland Clinic, Cleveland, OH 44195, USA.
Koji HashimotoTransplantation Center, Department of Liver Transplantation, Cleveland Clinic, Cleveland, OH 44195, USA.
Alejandro PitaTransplantation Center, Department of Liver Transplantation, Cleveland Clinic, Cleveland, OH 44195, USA.ORCID 0000-0003-2972-3782

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Liver transplantation is aptly described as the only curative treatment for cirrhosis and cirrhosis with co-morbid hepatocellular carcinoma (HCC). Its utility in the management of various other primary and secondary liver cancers is gaining traction rapidly, with more thorough assessments on broader populations continuing to emerge. Most prominently, this includes colorectal cancer liver metastasis (CRLM), cholangiocarcinoma (CCA), neuroendocrine tumors (NETs), and more. Furthermore, despite being a well described treatment for HCC for many years, growing evidence supports a change in oncological strategy for HCC, with broadened selection criteria and more advanced systemic and locoregional therapies available. Our review aims to describe the evidence supporting the expansion of indications and selection criteria for liver transplantation in various oncologic indications of primary and secondary liver tumors.

Indexed as

CCACRLMHCCliver transplantationtransplant oncology

Identifiers

PMID40075625
PMCPMC11898796

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.