Evidence map›Paper›PMID 40075477›Full record

ArticleMalaria journal2025

Through the eyes of the participant: using photovoice to understand the experiences and effects of ivermectin MDA in the context of the BOHEMIA clinical trial in Kwale, Kenya.

Truphena Onyango, Khadija Nuru, Karisa Kazungu, Winnie Wangari, Carlos Chaccour, N Regina Rabinovich, Joseph Mwangangi, Marta Maia, Caroline Jones

Abstract read
In one paragraph

Article in Malaria journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Truphena OnyangoKenya Medical Research Institute, Centre for Geographic Medicine Research-Coast, Kilifi, Kenya. Tnafula@kemri-wellcome.org.
Khadija NuruKenya Medical Research Institute, Centre for Geographic Medicine Research-Coast, Kilifi, Kenya.
Karisa KazunguKenya Medical Research Institute, Centre for Geographic Medicine Research-Coast, Kilifi, Kenya.
Winnie WangariKenya Medical Research Institute, Centre for Geographic Medicine Research-Coast, Kilifi, Kenya.
Carlos ChaccourISGlobal, Barcelona, Spain.
N Regina RabinovichISGlobal, Barcelona, Spain.
Joseph MwangangiKenya Medical Research Institute, Centre for Geographic Medicine Research-Coast, Kilifi, Kenya.
Marta MaiaKenya Medical Research Institute, Centre for Geographic Medicine Research-Coast, Kilifi, Kenya.
Caroline JonesKenya Medical Research Institute, Centre for Geographic Medicine Research-Coast, Kilifi, Kenya.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAssessing the acceptability of new malaria control interventions in clinical trials can be complex due to the need for strict ethical standards and specific trial procedures. While in-depth interviews and focus group discussions can provide useful insights, a more participatory method of data collection which complements these methods is photovoice. Photovoice offers a unique approach, empowering participants to share their experiences and perceptions on their own terms. Photovoice was employed alongside the BOHEMIA clinical trial (a trial investigating the safety and efficacy of ivermectin mass-drug administration (MDA) for malaria control) to explore participants' views on the trial and the effects of the intervention on individuals and communities.

methodsTwo participants from each of five villages involved in the trial (two intervention, three control) were purposively selected and trained on the ethical and technical use of cameras. During the final round of the intervention, participants photographed their trial experiences and the MDA effects. Two picture-sharing discussions were conducted to explore the picture content and reasons for their inclusion.

resultsBoth intervention and control groups expressed confidence in the trial procedures, with pictures capturing barcode scanning and health assessments, activities reported to provide reassurance and enhance trust. Photos from both groups showed positive outcomes such as improved appetite and fewer mosquitoes. However, photos from the ivermectin group also showed clearing of jiggers and killing of bed bugs. Images of rashes, described as a negative effect of the MDA, were taken by both groups. Pictures of mosquito breeding sites and sources of intestinal worms were also shared by both groups.

conclusionPhotovoice provided valuable insights into trial experiences, intervention effects, and revealed unexpected outcomes, such as killing of bedbugs, that warrant deeper exploration. It exposed broader community concerns of the source of malaria and intestinal worms not addressed by either the intervention or local health authorities.

Indexed as

IvermectinMalariaMass Drug AdministrationPhotographyAdolescentAdultFemaleHumansKenyaMaleMiddle AgedYoung AdultIvermectinIvermectinMalariaMDAMDA effectsNTDsPhotovoiceRandomised control trialsTrial experiences

Identifiers

PMID40075477
PMCPMC11905568

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.