Evidence map›Paper›PMID 40075367›Full record

ArticleBMC musculoskeletal disorders2025

The effectiveness of individualized blood flow restriction training following patellar fracture surgery: a case series.

Mingming Yang, Bin Liang, Xin Zhao, Yang Wang, Mingyuan Xue, Qipeng Song, Dan Wang

Registry-linked trialAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC musculoskeletal disorders, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05371431 (The Effect of Individualized Blood Flow Restriction Training on the Patients Following the Conservative Treatment of Distal Radius Fracture), which is not on this map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05371431 nacompletednot on this map

The Effect of Individualized Blood Flow Restriction Training on the Patients Following the Conservative Treatment of Distal Radius Fracture

TypeinterventionalSponsorNanjing First Hospital, Nanjing Medical UniversityRan2021 to 2021Enrolled25ConditionsDistal Radius FractureArmsTraditional rehabilitation training, Blood flow restriction combined with traditional rehabilitation training
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Mingming Yang *School of Athletic Performance, Shanghai University of Sport, 399 Changhai Road, Shanghai, 200082, China.
Bin Liang *Department of Orthopedics, Nanjing First Hospital, Nanjing, 210012, China.
Xin ZhaoDepartment of Orthopedics, Nanjing First Hospital, Nanjing, 210012, China.
Yang WangDepartment of Orthopedics, Nanjing First Hospital, Nanjing, 210012, China.
Mingyuan XueZimmer Biomet Inc, Shanghai, 200052, China.
Qipeng SongCollege of Sports and Health, Shandong Sport University, Shandong, 276827, China.
Dan WangSchool of Athletic Performance, Shanghai University of Sport, 399 Changhai Road, Shanghai, 200082, China. wangdan@sus.edu.cn.

Funding

Jiangsu Provincial Traditional Chinese Medicine Science and Technology Development YB201939Key Projects of Nanjing Health Science and Technology Development Special Fund ZKX19024Nanjing Medical University-Ximai Clinical Research Fund 2022-A-0029Natural Science Foundation of the Higher Education Institutions of Jiangsu Province 17KJB320008Overseas High-level Talents at Shanghai Institutions of Higher Learning TP2019072Shanghai Key Lab of Human Performance 11DZ2261100
6 · The paper itself

Abstract

backgroundPatellar fracture surgeries are associated with subsequent atrophy and weakness in the muscles of the lower limb. Individualized blood flow restriction training is progressively being recognized as a potential technique for improving muscular hypertrophy and accompanying strength in participants recovering from surgery. This study aimed to investigate the overall feasibility and observational outcomes of individualized blood flow restriction training for participants recovering from patellar fracture surgery.

methodsA 47-year-old male (Participant one, body mass: 65 kg, height: 1.75 m, body mass index: 21.2 kg/m

resultsCompared to baseline, the post-training peak torque of the knee extensor, rectus femoris cross-sectional area, rectus femoris stiffness, and Lysholm score of participants one post-surgical leg increased by 48.2%, 7.9%, 7.9%, and 23 points, respectively; those of participant two increased by 134.7%, 6.8%, 14.2%, and 30 points, respectively.

conclusionsThe results showed that the individualized blood flow restriction training was feasible and suggested promising outcomes for participants after surgery. Further research with a large sample size is required to flesh out and generalize the training program.

trial registrationThe Nanjing First Hospital's ethics committee accepted the research before testing. The clinical test was documented with clinicaltrials.gov (NCT05371431, Registered 08-20-2020, prospectively registered).

Indexed as

Blood Flow Restriction TherapyFractures, BonePatellaAdultFeasibility StudiesFemaleHumansMaleMiddle AgedMuscle StrengthQuadriceps MuscleRandomized Controlled Trials as TopicTreatment OutcomeBlood flow restrictionMuscle strengthMusculoskeletal rehabilitationPatellar fracture surgeryPost-surgical rehabilitation

Identifiers

PMID40075367
PMCPMC11899750

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.