ArticleBMC public health2025
Associations between exposure to brominated flame retardants and hyperlipidemia risk in U.S. Adults.
Article in BMC public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
4 citing papers in PubMed.
- The association between the red blood cell distribution width to albumin ratio with all-cause and cause-specific mortality in patients with hyperlipidemia: a cohort study based on NHANES 1999-2018.Irish journal of medical science · 2026Article
- Association between hyperuricemia and kidney stones in Southern China: a multicentre cross-sectional study.Frontiers in endocrinology · 2026Article
- Article
- Estimated glucose disposal rate and its dual role in hyperlipidemia risk and mortality: a secondary analysis of retrospective cohort data from U.S. and Chinese.Lipids in health and disease · 2025Article
Corrections and comments
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Authors and funding
14 authors.
Funding
Abstract
backgroundEnvironmental exposure to toxic brominated flame retardants (BFRs) has been confirmed to have detrimental effects on human health. The impact of serum BFRs on hyperlipidemia risk has not been sufficiently examined. Our objective is to identify both the individual and combined effects of serum BFRs on hyperlipidemia and to further investigate the most influential chemicals.
methodsWe included 7,009 individuals with complete details on 9 types of serum BFRs, hyperlipidemia, and other covariates from the NHANES in 2007-2016. Multivariate logistic regression was conducted to evaluate the individual impact of BFRs exposure on hyperlipidemia risk. We assessed the cumulative effect of BFRs on hyperlipidemia risk through weighted quantile sum (WQS) regression, quantile g-computation (QGC), and Bayesian kernel machine regression models.
resultsPBDE 28, PBDE 47, PBDE 85, PBDE 99, PBDE 100, PBDE 154, PBDE 209, and PBB153 were found to be positively associated with hyperlipidemia risk. The results of WQS and QGC revealed consistent positive correlation. PBDE209 emerged as the most significant chemicals exerting influence. The restricted cubic splines regression further identified significant dose-response relationship.
conclusionExposure to individual and combined serum BFRs has been associated with an increased risk of hyperlipidemia. The causal relationship still requires confirmation through large-scale cohort studies.
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