Evidence map›Paper›PMID 40075141›Full record

ArticleNPJ precision oncology2025

Integrative whole slide image and spatial transcriptomics analysis with QuST and QuPath.

Chao-Hui Huang, Sara Lichtarge, Diane Fernandez

Abstract read
In one paragraph

Article in NPJ precision oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Chao-Hui HuangOncology Research & Development, Pfizer Inc., 10777 Science Center Dr., San Diego, CA, 92121, USA. chao-hui.huang@pfizer.com.ORCID http://orcid.org/0000-0002-3837-8135
Sara LichtargeOncology Research & Development, Pfizer Inc., 10777 Science Center Dr., San Diego, CA, 92121, USA.ORCID http://orcid.org/0009-0009-0603-9997
Diane FernandezOncology Research & Development, Pfizer Inc., 10777 Science Center Dr., San Diego, CA, 92121, USA.ORCID http://orcid.org/0000-0003-1365-5172

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The integration of AI in digital pathology, particularly in whole slide image (WSI) and spatial transcriptomics (ST) analysis, holds immense potential for enhancing disease understanding. Despite challenges such as training pattern preparation and resolution disparities, the convergence of these technologies can unlock insights. We introduce QuST, a QuPath extension that bridges the gap between WSI and ST at single-cell level, highlighting the power of this integrated approach in disease biology.

Identifiers

PMID40075141
PMCPMC11904241

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.