Evidence map›Paper›PMID 40075014›Full record

ArticleChild's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery2025

Postoperative word-finding difficulties in children with posterior fossa tumours: a crosslinguistic European cohort study.

K Persson, J Grønbæk, I Tiberg, Å Fyrberg, C Castor, B Andreozzi, R Frič, P Hauser, R Kiudeliene, C Mallucci and 6 more

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Article in Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

16 authors.

K PerssonDepartment of Health Sciences, Lund University, Lund, Sweden. karin.persson.2084@med.lu.se.
J GrønbækDepartment of Paediatric and Adolescent Medicine, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark.
I TibergDepartment of Health Sciences, Lund University, Lund, Sweden.
Å FyrbergDepartment of Speech and Language Pathology, University of Gothenburg, Gothenburg, Sweden.
C CastorDepartment of Health Sciences, Lund University, Lund, Sweden.
B AndreozziDepartment of Oncology/Hematology, Cell Therapy Gene Therapies and Hemopoietic Transplant, Scientific Institute for Research, Hospitalization and Healthcare Bambino Gesù Children's Hospital, Rome, Italy.
R FričDepartment of Neurosurgery, Oslo University Hospital Rikshospitalet, Oslo, Norway.
P HauserDepartment of Pediatrics, Semmelweis University, Budapest, Hungary.
R KiudelieneDepartment of Pediatrics, Lithuanian University of Health Sciences, Kaunas, Lithuania.
C MallucciDepartment of Neurosurgery, Alder Hey Children's NHS trust, Liverpool, UK.
R MathiasenDepartment of Clinical Medicine, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark.
P NymanCrown Princess Victoria Children's Hospital and Department of Biomedical and Clinical Sciences, Linköping University, Linköping, Sweden.
B PizerUniversity of Liverpool, Liverpool, UK.
A SehestedDepartment of Paediatric and Adolescent Medicine, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark.
D Boeg ThomsenDepartment of Nordic Studies and Linguistics, University of Copenhagen, Copenhagen, Denmark.
CMS study group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposePosterior fossa tumour (PFT) surgery carries a risk of mutism or severely reduced speech. As for higher-cognitive language functions, word-finding difficulties have been reported, but no study has compared pre- and postoperative word-finding speeds to identify impairment caused by surgery. The current study investigated changes in word-finding ability associated with PFT surgery and examined factors affecting postoperative ability.

methodWe included 184 children aged 5:0-17:9 years undergoing PFT surgery and assessed word-finding ability before and after surgery using a speeded picture-naming test. We compared postoperative word-finding performance with both preoperative performance and age-specific norms and examined factors affecting word-finding ability.

resultsWe found no significant difference between pre- and postoperative performance, reflecting that some children exhibited better word-finding ability after surgery, others poorer. After surgery, 95% of the children performed two standard deviations above (slower than) age-specific norms. Tumour location in the fourth ventricle negatively affected postoperative word-finding ability (B = -4.09, p < 0.05).

conclusionFor some children, PFT surgery leads to postoperative word-finding difficulties, emphasizing the importance of postoperative language assessments and interventions. Fourth-ventricle tumour location emerged as a risk factor for poorer postoperative word-finding ability, likely reflecting surgical damage to the dentato-thalamo-cortical pathway (DTCP).

Indexed as

Infratentorial NeoplasmsNeurosurgical ProceduresPostoperative ComplicationsAdolescentChildChild, PreschoolCohort StudiesEuropeFemaleHumansMaleCerebellar mutism syndromeChild languageLanguage impairmentPosterior fossa tumourPostoperative speech impairment (POSI)Word-finding difficulties

Identifiers

PMID40075014
PMCPMC11903548

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.