Evidence map›Paper›PMID 40074902›Full record

ArticleNature2025

A robustly rooted tree of eukaryotes reveals their excavate ancestry.

Kelsey Williamson, Laura Eme, Hector Baños, Charley G P McCarthy, Edward Susko, Ryoma Kamikawa, Russell J S Orr, Sergio A Muñoz-Gómez, Bui Quang Minh, Alastair G B Simpson and 1 more

Abstract read
PubMed Publisher
In one paragraph

Article in Nature, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers.

0numbers the graph read from it
0cells of the map it votes in
53citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

53 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Environmental phylogenetics supports a steady diversification of crown eukaryotes starting from the mid-Proterozoic.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  6. Article
  7. Review
  8. Article
  9. Reversal to osmotrophy in eukaryotes.Nature ecology & evolution · 2026
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Evolutionary Analysis of Trehalose Breakdown Pathways.Genome biology and evolution · 2026
    Article
  16. Review
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Kelsey WilliamsonDepartment of Biochemistry and Molecular Biology and Institute for Comparative Genomics, Dalhousie University, Halifax, Nova Scotia, Canada. k.williamson@dal.ca.ORCID 0000-0001-5512-8413
Laura EmeDepartment of Biochemistry and Molecular Biology and Institute for Comparative Genomics, Dalhousie University, Halifax, Nova Scotia, Canada.
Hector BañosDepartment of Biochemistry and Molecular Biology and Institute for Comparative Genomics, Dalhousie University, Halifax, Nova Scotia, Canada.
Charley G P McCarthyDepartment of Biochemistry and Molecular Biology and Institute for Comparative Genomics, Dalhousie University, Halifax, Nova Scotia, Canada.ORCID 0000-0002-3880-9978
Edward SuskoDepartment of Mathematics and Statistics and Institute for Comparative Genomics, Dalhousie University, Halifax, Nova Scotia, Canada.
Ryoma KamikawaGraduate School of Agriculture, Kyoto University, Kyoto, Japan.ORCID 0000-0003-2648-8107
Russell J S OrrSection for Genetics and Evolutionary Biology, Department of Biosciences, University of Oslo, Oslo, Norway.
Sergio A Muñoz-GómezDepartment of Biochemistry and Molecular Biology and Institute for Comparative Genomics, Dalhousie University, Halifax, Nova Scotia, Canada.
Bui Quang MinhSchool of Computing, Australian National University, Canberra, Australian Capital Territory, Australia.ORCID 0000-0002-5535-6560
Alastair G B SimpsonDepartment of Biology and Institute for Comparative Genomics, Dalhousie University, Halifax, Nova Scotia, Canada.
Andrew J RogerDepartment of Biochemistry and Molecular Biology and Institute for Comparative Genomics, Dalhousie University, Halifax, Nova Scotia, Canada. andrew.roger@dal.ca.ORCID 0000-0003-1370-9820

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The eukaryote Tree of Life (eToL) depicts the relationships among all eukaryotic organisms; its root represents the Last Eukaryotic Common Ancestor (LECA) from which all extant complex lifeforms are descended

Indexed as

EukaryotaEukaryotic CellsPhylogenyAnimalsMitochondrial ProteinsMitochondrial Proteins

Identifiers

PMID40074902

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.