Evidence map›Paper›PMID 40074426›Full record

ArticleJournal, genetic engineering & biotechnology2025

Comprehensive evaluation of antibacterial and anticancer activities from indole butanoic acid.

Azhar H Ali, Mohanad Yakdhan Saleh, Qusay Abdulazahra Yaqoob, Shakir M Saied, Mohammed Sami Hasan, Khalid Ahmed Owaid, Basma A A Balboul, Heba G Abdelzaher, M A Abdelzaher, Alaa Muqbil Alsirhani

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal, genetic engineering & biotechnology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Azhar H AliTaq Harb Intermediate School for Boys, Directorate of Education in Nineveh, Ministry of Education, Mosul, Iraq.
Mohanad Yakdhan SalehDepartment of Chemistry, College of Education for Pure Science, University of Mosul, Ministry of Higher Education and Scientific Research, Mosul, Iraq.
Qusay Abdulazahra YaqoobDepartment of Surgery, College of Medicine, University of Kufa, Al-Kufa Street, Najaf, Iraq.
Shakir M SaiedCollege of Pharmacy, Al Noor University, Al-Shallalat Road, Nineveh, Iraq.
Mohammed Sami HasanAnesthesia Techniques Department, College of Health and Medical Techniques, Al-Mustaqbal University, 51001 Babylon, Iraq.
Khalid Ahmed OwaidDepartment of Chemistry, College of Education for Pure Science, University of Mosul, Ministry of Higher Education and Scientific Research, Mosul, Iraq.
Basma A A BalboulDepartment of Chemistry, College of Sciences, Jouf University, PO Box 72341, Sakaka, Saudi Arabia.
Heba G AbdelzaherDepartment of Clinical Pharmacy, Faculty of Pharmacy, Minia University, 61519 Minia, Egypt.
M A AbdelzaherAnesthesia Techniques Department, College of Health and Medical Techniques, Al-Mustaqbal University, 51001 Babylon, Iraq; Department of Chemistry, College of Sciences, Jouf University, PO Box 72341, Sakaka, Saudi Arabia; Department of Clinical Pharmacy, Faculty of Pharmacy, Minia University, 61519 Minia, Egypt; Environmental Science and Industrial Development Department, Faculty of Postgraduate Studies for Advanced Sciences, Beni-Suef University, Beni-Suef 62511, Egypt. Electronic address: M.abuelseoud@psas.bsu.edu.eg.
Alaa Muqbil AlsirhaniDepartment of Chemistry, College of Sciences, Jouf University, PO Box 72341, Sakaka, Saudi Arabia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Focus of this study is on the use of the hydrazone compound (3) (N-(4-bromobenzylidene)-4-(1H-indol-3-yl) butane hydrazide), which was previously prepared from the reaction of the compound p-bromobenzaldehyde with the corresponding hydrazide (2), as an intermediate compound for the synthesis of azetidine, thiazolidine, tetrazole, oxadiazole and phthalazine heterocyclic compounds through its reaction with some cyclic reagents and catalysts such as chloro acetyl chloride, thioglycolic acid, sodium-azid, lead dioxide and Hydrogen chloride gas. The prepared compounds were characterized using physical properties and also spectroscopic methods such as infrared spectroscopy, nuclear magnetic resonance spectra of the proton and the isotope of carbon

Indexed as

Biological Antibacterial EvaluationMTT and Anticancer ActivateOxathiazolidineOxoazetidinePhthalazineTetrazole

Identifiers

PMID40074426
PMCPMC11732482

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.