Evidence map›Paper›PMID 40074329›Full record

ArticleAnaesthesia2025

Surgery in patients aged ≥ 80 years: mortality and recovery in a nationwide cohort study.

Jesper Eriksson, Cornelia Sandberg, Naima Kilhamn, Max Bell, Anders Oldner, Emma Larsson

Abstract read
In one paragraph

Article in Anaesthesia, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Frailty in anesthesia.Current opinion in anaesthesiology · 2026
    Review
  5. Article
  6. Article
  7. Subclinical Hepatic Injury and Dysfunction Following Surgery: Evidence From a Young and Aged Laparotomy Murine Model.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2025
    Article
  8. Observational
  9. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jesper ErikssonSection of Anesthesiology and Intensive Care Medicine, Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm, Sweden.ORCID 0000-0002-5219-8368
Cornelia SandbergPerioperative Medicine and Intensive Care, Karolinska University Hospital, Stockholm, Sweden.
Naima KilhamnSection of Anesthesiology and Intensive Care Medicine, Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm, Sweden.
Max BellSection of Anesthesiology and Intensive Care Medicine, Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm, Sweden.
Anders OldnerSection of Anesthesiology and Intensive Care Medicine, Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm, Sweden.
Emma LarssonSection of Anesthesiology and Intensive Care Medicine, Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm, Sweden.

Funding

Baxter MedicalFredrik & Ingrid Thurings' FoundationRegion StockholmStiftelsen SerafimerlasarettetThe Swedish Heart Lung FoundationThe Swedish Society of Medicine
6 · The paper itself

Abstract

introductionAs the global population ages, the demand for surgical interventions in older adults is rising. Older patients face increased risks due to age-related physiological changes and comorbidities, making surgery and postoperative care challenging. This study aimed to assess short- and long-term mortality, as well as patient-centred outcomes such as days alive and at home 30 and 90 days after surgery, in patients aged ≥ 80 y undergoing surgical procedures.

methodsThis nationwide cohort study utilised data from the Swedish Perioperative Register, including surgeries in patients aged ≥ 80 y in Sweden from January 2019 to March 2023. We linked peri-operative data with the National Patient Register for comorbidities and with the National Cause of Death Register. The primary outcome was all-cause 30-day mortality, with secondary outcomes of 365-day mortality and days alive and at home 30 and 90 days after surgery.

resultsA total of 118,359 patients were included, with 54,320 undergoing elective and 64,039 acute surgeries. Thirty-day mortality was 1.2% for elective and 9.9% for acute surgeries. Mortality increased significantly with age, particularly for patients aged ≥ 90 y compared with those aged 80-84 y. Days alive and at home 30 and 90 days after surgery were significantly lower for acute surgery patients, indicating longer recovery times and more postoperative complications. DISCUSSION: Older adults, especially those aged ≥ 90 y, experience high mortality and significant challenges in postoperative recovery after acute surgeries. Elective surgeries are associated with lower short-term mortality, suggesting that age alone should not preclude surgical interventions. Tailored peri-operative care and patient-centred decision-making are essential to improve outcomes in this vulnerable population.

Indexed as

Surgical Procedures, OperativeAged, 80 and overAge FactorsCohort StudiesFemaleHumansMalePostoperative ComplicationsRegistriesSwedenepidemiologygeriatricmortalitypostoperativesurgery

Identifiers

PMID40074329
PMCPMC12171789

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.