Evidence map›Paper›PMID 40074323›Full record

ArticleJournal of medical ethics2026

Large language models for surgical informed consent: an ethical perspective on simulated empathy.

Pranab Rudra, Wolf-Tilo Balke, Tim Kacprowski, Frank Ursin, Sabine Salloch

Abstract read
In one paragraph

Article in Journal of medical ethics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Digital bioethics: exploring an emerging field.Medicine, health care, and philosophy · 2026
    Article
  5. Article
  6. Article
  7. Nothing in life is to be feared; it is only to be understood.Advances in ophthalmology practice and research
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Pranab RudraInstitute for Ethics, History and Philosophy of Medicine, Hannover Medical School, Hannover, Germany pranab.rudra@stud.mh-hannover.de.ORCID http://orcid.org/0000-0002-1953-9909
Wolf-Tilo BalkeInstitute for Information Systems (IfIS), TU Braunschweig , Braunschweig, Germany.
Tim KacprowskiDivision Data Science in Biomedicine, Peter L. Reichertz Institute for Medical Informatics of Technische Universität Braunschweig and Hannover Medical School, TU Braunschweig, Braunschweig, Niedersachsen, Germany.
Frank UrsinInstitute for Ethics, History and Philosophy of Medicine, Hannover Medical School, Hannover, Germany.ORCID http://orcid.org/0000-0002-9378-3811
Sabine SallochInstitute for Ethics, History and Philosophy of Medicine, Hannover Medical School, Hannover, Germany.ORCID http://orcid.org/0000-0002-2987-2684

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Informed consent in surgical settings requires not only the accurate communication of medical information but also the establishment of trust through empathic engagement. The use of large language models (LLMs) offers a novel opportunity to enhance the informed consent process by combining advanced information retrieval capabilities with simulated emotional responsiveness. However, the ethical implications of simulated empathy raise concerns about patient autonomy, trust and transparency. This paper examines the challenges of surgical informed consent, the potential benefits and limitations of digital tools such as LLMs and the ethical implications of simulated empathy. We distinguish between active empathy, which carries the risk of creating a misleading illusion of emotional connection and passive empathy, which focuses on recognising and signalling patient distress cues, such as fear or uncertainty, rather than attempting to simulate genuine empathy. We argue that LLMs should be limited to the latter, recognising and signalling patient distress cues and alerting healthcare providers to patient anxiety. This approach preserves the authenticity of human empathy while leveraging the analytical strengths of LLMs to assist surgeons in addressing patient concerns. This paper highlights how LLMs can ethically enhance the informed consent process without undermining the relational integrity essential to patient-centred care. By maintaining transparency and respecting the irreplaceable role of human empathy, LLMs can serve as valuable tools to support, rather than replace, the relational trust essential to informed consent.

Indexed as

EmpathyInformed ConsentLanguagePhysician-Patient RelationsSurgical Procedures, OperativeCommunicationEmotionsHumansLarge Language ModelsPatient-Centered CareTrustEthicsEthics- MedicalHealth PersonnelInformed ConsentPersonal Autonomy

Identifiers

PMID40074323
PMCPMC12911618

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.