Evidence map›Paper›PMID 40073519›Full record

ArticleSocial science & medicine (1982)2025

Midlife financial stress and cognitive and physical impairments in older age: The role of potentially modifying factors.

Ingemar Kåreholt, Charlotta Nilsen, Miia Kivipelto, Deborah Finkel, Shireen Sindi

Abstract read
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Article in Social science & medicine (1982), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

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3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

5 authors.

Ingemar KåreholtInstitute of Gerontology, School of Health and Welfare, Aging Research Network - Jönköping (ARN-J), Jönköping University, Jönköping, Sweden; Division of Clinical Geriatrics, Center for Alzheimer's Research, Department of Neurobiology, Care Sciences and Society (NVS), Karolinska Institutet and Karolinska University Hospital, Stockholm, Sweden; Aging Research Center (ARC), Department of Neurobiology, Care Sciences and Society (NVS), Karolinska Institutet/Stockholm University, Stockholm, Sweden. Electronic address: ingemar.kareholt@ju.se.
Charlotta NilsenInstitute of Gerontology, School of Health and Welfare, Aging Research Network - Jönköping (ARN-J), Jönköping University, Jönköping, Sweden; Aging Research Center (ARC), Department of Neurobiology, Care Sciences and Society (NVS), Karolinska Institutet/Stockholm University, Stockholm, Sweden; Stress Research Institute, Department of Psychology, Stockholm University, Stockholm, Sweden.
Miia KivipeltoDivision of Clinical Geriatrics, Center for Alzheimer's Research, Department of Neurobiology, Care Sciences and Society (NVS), Karolinska Institutet and Karolinska University Hospital, Stockholm, Sweden; Theme Inflammation and Aging. Karolinska University Hospital, Stockholm, Sweden; Institute of Public Health and Clinical Nutrition, University of Eastern Finland, Kuopio, Finland; Ageing Epidemiology Research Unit (AGE), School of Public Health, Faculty of Medicine, Imperial College London, London, United Kingdom.
Deborah FinkelInstitute of Gerontology, School of Health and Welfare, Aging Research Network - Jönköping (ARN-J), Jönköping University, Jönköping, Sweden; Center for Economic and Social Research, University of Southern California, Los Angeles, CA, USA.
Shireen SindiDivision of Clinical Geriatrics, Center for Alzheimer's Research, Department of Neurobiology, Care Sciences and Society (NVS), Karolinska Institutet and Karolinska University Hospital, Stockholm, Sweden; Ageing Epidemiology Research Unit (AGE), School of Public Health, Faculty of Medicine, Imperial College London, London, United Kingdom.

Funding

Differences in the association of education with ADRD across countries, historical eras, and men and women.R01AG081248 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI DEBORAH G FINKEL, Brian K. Finch · 2024 to 2026
$3.6M
NIA NIH HHS R01 AG081248
6 · The paper itself

Abstract

backgroundFinancial stress is an important source of chronic stress and has been associated with cognitive and physical impairments. The goal of this study was to investigate whether financial stress is associated with cognitive and physical impairment and their combination, the role of potential modifiable factors and potential sex differences.

methodsThe Cardiovascular Risk Factors, Aging, and Dementia population-based cohort study from Finland was used (n = 1497) (baseline data collected 1972-1987, mean age 50 years). Two late-life re-examinations (mean total follow-up 21 years). Midlife financial stress was measured using two questions on financial situation. Cognitive functioning was based on six cognitive domains. Physical impairment was self-reported, including activities of daily living and mobility. Potential mediation factors investigated were smoking, alcohol, physical activity, cohabitant status, non-manual work, and sleep disturbances. Sex differences were investigated. We used path analyses with full information maximum likelihood estimation.

resultsMidlife financial stress was associated with worse cognitive functioning, physical impairment and their combination. Smoking and sleep disturbances mediated the associations between financial stress, physical impairment, and combined impairments. For men: Among smokers financial stress was associated with worse cognitive functioning; alcohol interacted with financial stress on combined impairments; cohabitation and non-manual work mediated associations to worse cognitive functioning. Among women, sleep disturbances moderated the association to worse cognitive functioning.

conclusionsMidlife financial stress is associated with late-life impairments, and lifestyle/sociodemographic factors may modify these associations. Sex differences were observed. Interventions promoting healthier lifestyle and psychosocial factors may buffer against the deleterious role of financial stress.

Indexed as

Financial StressActivities of Daily LivingAgedCohort StudiesFemaleFinlandHumansMaleMiddle AgedRisk FactorsSex FactorsSmokingAgingCognitionFinancial strainLifestyleLongitudinalMediationPhysical functionSex differences

Identifiers

PMID40073519
PMCPMC12801007

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.