Evidence map›Paper›PMID 40073137›Full record

ArticleScience advances2025

Shear flow patterns antimicrobial gradients across bacterial populations.

Alexander M Shuppara, Gilberto C Padron, Anuradha Sharma, Zil Modi, Matthias D Koch, Joseph E Sanfilippo

Abstract read
In one paragraph

Article in Science advances, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Detoxification of host-relevant HbioRxiv : the preprint server for biology · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Alexander M ShupparaDepartment of Biochemistry, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.ORCID 0000-0002-0838-637X
Gilberto C PadronDepartment of Biochemistry, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.ORCID 0000-0002-5006-9159
Anuradha SharmaDepartment of Biochemistry, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.
Zil ModiDepartment of Biology, Texas A&M University, College Station, TX 77843, USA.
Matthias D KochDepartment of Biology, Texas A&M University, College Station, TX 77843, USA.ORCID 0000-0003-4408-9900
Joseph E SanfilippoDepartment of Biochemistry, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.ORCID 0000-0002-8775-5179

Funding

Bacterial stress responses and surface adhesion in shear flowR35GM155443 · NIGMS · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI Joseph Sanfilippo · 2024 to 2026
$1.1M
Mechanobehavior of Pseudomonas aeruginosa in shear flowK22AI151263 · NIAID · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI SANFILIPPO, JOSEPH · 2021 to 2022
$267k
NIAID NIH HHS K22 AI151263NIGMS NIH HHS R35 GM155443
6 · The paper itself

Abstract

Bacterial populations experience chemical gradients in nature. However, most experimental systems either ignore gradients or fail to capture gradients in mechanically relevant contexts. Here, we use microfluidic experiments and biophysical simulations to explore how host-relevant shear flow affects antimicrobial gradients across communities of the highly resistant pathogen

Indexed as

Anti-Bacterial AgentsAnti-Infective AgentsBacteriaPseudomonas aeruginosaGentamicinsHydrogen PeroxideMicrobial Sensitivity TestsMicrofluidicsAnti-Bacterial AgentsAnti-Infective AgentsGentamicinsHydrogen Peroxide

Identifiers

PMID40073137
PMCPMC11900875

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.