Evidence map›Paper›PMID 40073129›Full record

ArticleScience advances2025

FlyVISTA, an integrated machine learning platform for deep phenotyping of sleep in

Mehmet F Keleş, Ali Osman Berk Sapci, Casey Brody, Isabelle Palmer, Anuradha Mehta, Shahin Ahmadi, Christin Le, Öznur Taştan, Sündüz Keleş, Mark N Wu

Abstract read
In one paragraph

Article in Science advances, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Invertebrate brains as diversified models for understanding sleep mechanisms and function.Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology · 2026
    Review
  3. Article
  4. Autobehaver: An AI-Based Pipeline for Animal Behavior Analysis.bioRxiv : the preprint server for biology · 2026
    Article
  5. Article
  6. Inferring the genetic basis of sleep states inbioRxiv : the preprint server for biology · 2026
    Article
  7. Current Evidence for Sleep States inCurrent sleep medicine reports · 2026
    Review
  8. 25 years ofFly · 2025
    Review
  9. Recognition of distinct sleep states inbioRxiv : the preprint server for biology · 2025
    Article
  10. Neurobiology of mitochondrial dynamics in sleep.The Journal of physiology · 2025
    Review
  11. Royal Society open science · 2025
    Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors.

Mehmet F KeleşDepartment of Neurology, Johns Hopkins University, Baltimore, MD 21205, USA.ORCID 0000-0001-6673-1613
Ali Osman Berk SapciDepartment of Computer Science, Sabanci University, Tuzla, Istanbul 34956, Turkey.ORCID 0000-0003-4396-817X
Casey BrodyDepartment of Neurology, Johns Hopkins University, Baltimore, MD 21205, USA.
Isabelle PalmerDepartment of Neurology, Johns Hopkins University, Baltimore, MD 21205, USA.ORCID 0000-0001-5676-4737
Anuradha MehtaDepartment of Neurology, Johns Hopkins University, Baltimore, MD 21205, USA.
Shahin AhmadiDepartment of Neurology, Johns Hopkins University, Baltimore, MD 21205, USA.
Christin LeDepartment of Neurology, Johns Hopkins University, Baltimore, MD 21205, USA.ORCID 0009-0005-0845-0879
Öznur TaştanDepartment of Computer Science, Sabanci University, Tuzla, Istanbul 34956, Turkey.
Sündüz KeleşDepartment of Biostatistics and Medical Informatics, University of Wisconsin-Madison, Madison, WI 53706, USA.
Mark N WuDepartment of Neurology, Johns Hopkins University, Baltimore, MD 21205, USA.ORCID 0000-0002-1329-0655

Funding

Cross-Species Analyses of the Molecular and Circuit Basis ofSleepR35NS122181 · NINDS · JOHNS HOPKINS UNIVERSITY · PI Mark N Wu · 2021 to 2026
$6.9M
Statistical Methods for the Analysis of ChlP-chip DataR01HG003747 · NHGRI · UNIVERSITY OF WISCONSIN-MADISON · PI KELES, SUNDUZ · 2007 to 2024
$4.8M
Statistical methods for co-expression network analysis of population-scale scRNA-seq dataR21HG012881 · NHGRI · UNIVERSITY OF WISCONSIN-MADISON · PI KELES, SUNDUZ · 2023 to 2023
$408k
The Function of Sleep in Critical Period PlasticityK99NS124976 · NINDS · JOHNS HOPKINS UNIVERSITY · PI KELES, MEHMET · 2023 to 2024
$191k
NHGRI NIH HHS R01 HG003747NHGRI NIH HHS R21 HG012881NINDS NIH HHS K99 NS124976NINDS NIH HHS R35 NS122181
6 · The paper itself

Abstract

There is great interest in using genetically tractable organisms such as

Indexed as

Deep LearningDrosophilaDrosophila melanogasterMachine LearningSleepAnimalsBehavior, AnimalPhenotype

Identifiers

PMID40073129
PMCPMC11900856

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.