ArticleeLife2025
Using normative models pre-trained on cross-sectional data to evaluate intra-individual longitudinal changes in neuroimaging data.
Article in eLife, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed.
- Perinatal Factors and Neuroimaging Changes for Brain Maturation Among Adolescents.JAMA network open · 2026Article
- Aging and metabolism contribute separately to brain-body health.PLoS biology · 2026Article
- Normative age-related structural brain deviations underlying psychopathology, cognitive impairment and neurological soft signs in schizophrenia spectrum disorders.Translational psychiatry · 2026Article
- Spatially and temporally progressive hypoperfusion in Alzheimer's disease revealed by normative modeling.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Article
- Leveraging Longitudinal Data to Improve BrainChart Calibration for Small Study Sample Sizes.Human brain mapping · 2026Article
- Predicting developmental norms from baseline cortical thickness in longitudinal studies.Biology of sex differences · 2026Article
- Article
- Understanding individual neurodegenerative progression in Parkinson's disease through normative modelling.Scientific reports · 2025Article
- Towards precision MRI biomarkers in epilepsy with normative modelling.Brain : a journal of neurology · 2025Review
- Heterogeneity of morphometric similarity networks in health and schizophrenia.Schizophrenia (Heidelberg, Germany) · 2025Article
- Brain morphology normative modelling platform for abnormality and centile estimation: Brain MoNoCle.Imaging neuroscience (Cambridge, Mass.) · 2025Article
- Moving beyond diagnostic labels in psychiatry: outcome-linked treatment modelling.General psychiatry · 2025Article
- Learning Latent Profiles via Cognitive Growth Charting in Psychosis: Design and Rationale for the PRECOGNITION Project.Schizophrenia bulletin open · 2025Article
- Longitudinal alterations in brain networks and thalamocortical connectivity in paediatric focal epilepsy: a structural connectomics pilot study.Brain communications · 2025Article
- Psychiatric neuroimaging designs for individualised, cohort, and population studies.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2024Review
- Personalizing progressive changes to brain structure in Alzheimer's disease using normative modeling.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024Article
- Dissecting task-based fMRI activity using normative modelling: an application to the Emotional Face Matching Task.Communications biology · 2024Article
- Population-wide cerebellar growth models of children and adolescents.Nature communications · 2024Article
- Estimating cortical thickness trajectories in children across different scanners using transfer learning from normative models.Human brain mapping · 2024Article
- The nature of grief: implications for the neurobiology of emotion.Neuroscience of consciousness · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
Abstract
Longitudinal neuroimaging studies offer valuable insight into brain development, ageing, and disease progression over time. However, prevailing analytical approaches rooted in our understanding of population variation are primarily tailored for cross-sectional studies. To fully leverage the potential of longitudinal neuroimaging, we need methodologies that account for the complex interplay between population variation and individual dynamics. We extend the normative modelling framework, which evaluates an individual's position relative to population standards, to assess an individual's longitudinal
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.