Evidence map›Paper›PMID 40072830›Full record

ArticleCell biochemistry and biophysics2025

Cytochrome c and Ouabain Binding Site of Na,K-ATPase.

Gvantsa Chkadua, Eka Nozadze, Leila Tsakadze, Lia Shioshvili, Marine Leladze, Nana Arutinova, Sopio Dzneladze, Maia Javakhishvili, Tamar Jariashvili

Abstract readLetter
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In one paragraph

Article in Cell biochemistry and biophysics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Combined UV and Formic Acid Treatment SuppressesFoods (Basel, Switzerland) · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Gvantsa ChkaduaIvane Beritashvili Center of Experimental Biomedicine, 14 Gotua Str., Tbilisi, Georgia. g.chkadua@biomedicine.org.ge.
Eka NozadzeIvane Beritashvili Center of Experimental Biomedicine, 14 Gotua Str., Tbilisi, Georgia.
Leila TsakadzeIvane Beritashvili Center of Experimental Biomedicine, 14 Gotua Str., Tbilisi, Georgia.
Lia ShioshviliIvane Beritashvili Center of Experimental Biomedicine, 14 Gotua Str., Tbilisi, Georgia.
Marine LeladzeIvane Beritashvili Center of Experimental Biomedicine, 14 Gotua Str., Tbilisi, Georgia.
Nana ArutinovaIvane Beritashvili Center of Experimental Biomedicine, 14 Gotua Str., Tbilisi, Georgia.
Sopio DzneladzeIvane Beritashvili Center of Experimental Biomedicine, 14 Gotua Str., Tbilisi, Georgia.
Maia JavakhishviliIvane Beritashvili Center of Experimental Biomedicine, 14 Gotua Str., Tbilisi, Georgia.
Tamar JariashviliGeorgian National University, 9 Tsinandali Str., Tbilisi, Georgia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Na,K-ATPase is an electrogenic pump found in cell plasma membranes that acts as the basic unit of animal life. This enzyme is highly susceptible to cardiotonic steroid (CTS) inhibition. The role of Na,K-ATPase in signaling has introduced a novel viewpoint regarding the enzyme's function, as the ouabain-binding site is involved in several physiological processes. At high concentrations, ouabain blocks Na

Indexed as

Cytochromes cOuabainSodium-Potassium-Exchanging ATPaseAnimalsBinding SitesHippocampusKineticsMaleRatsCytochromes cOuabainSodium-Potassium-Exchanging ATPaseCysteineCytochrome cNa,K-ATPaseOuabain binding site

Identifiers

PMID40072830

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.