ArticleAnnals of surgical oncology2025
Money Matters: The Effect of Income on Postsurgical Outcomes in Stage IA Non-small Cell Lung Cancer.
Article in Annals of surgical oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Financial toxicity among patients with lung cancer: a systematic review and meta-analysis.Frontiers in public health · 2026Pooled it
- The value of prognostic immune-inflammatory-nutritional score in predicting survival after surgery in stage I-III non-small cell lung cancer.Journal of thoracic disease · 2025Article
Corrections and comments
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Authors and funding
13 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTreatment of non-small cell lung cancer (NSCLC) remains challenging; 5-year survival is as low as 24% for resectable disease. However, the outlook for stage IA NSCLC is favorable, with 5-year survival exceeding 74% and with surgery often being curative. Despite this positive prognosis, low socioeconomic status has been shown to correlate with nonstandard treatment and worse overall survival specifically in stage IA. This study sought to examine income-based disparities in postsurgical survival which has yet to be discussed in the current literature.
methodsThe National Cancer Database was retrospectively queried from 2004 to 2017 to identify patients with pathological stage IA NSCLC following surgical resection; survival/patient characteristics were analyzed by income quartiles and eras (2004-2007, 2008-2012, and 2013-2017). Kaplan-Meier methods and multivariable Cox hazard modeling were used to estimate survival and construct hazard ratios, respectively.
resultsInclusion criteria identified 138,219 patients. Overall, a stepwise decrease in 5-year survival was observed as income quartile decreased (Q4: 72.0%; Q3: 67.8%; Q2: 66.1%; Q1: 64.2%). Hazard modeling implicated income level as an independent predictor of mortality; patients of the lowest income quartile exhibited a hazard ratio of 1.26 (95% confidence interval 1.21-1.31; p < 0.001) relative to the highest. Although overall survival increased within each income quartile over consecutive eras, income-based survival disparities continued to be observed.
conclusionsLower-income patients with stage IA NSCLC display elevated mortality risk over 5 years than higher-income patients despite receiving potentially curative surgery, with income being an independent risk-factor. This difference may also be attributed to stacked risk-factors in lower-income patients.
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