Evidence map›Paper›PMID 40072715›Full record

ArticleJapanese journal of radiology2025

Super-resolution deep learning reconstruction for improved quality of myocardial CT late enhancement.

Masafumi Takafuji, Kakuya Kitagawa, Sachio Mizutani, Akane Hamaguchi, Ryosuke Kisou, Kenji Sasaki, Yuto Funaki, Kotaro Iio, Kazuhide Ichikawa, Daisuke Izumi and 3 more

Abstract read
In one paragraph

Article in Japanese journal of radiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Masafumi TakafujiDepartment of Radiology, Mie University Graduate School of Medicine, 2-174 Edobashi, Tsu, Mie, 514-8507, Japan.
Kakuya KitagawaDepartment of Radiology, Mie University Graduate School of Medicine, 2-174 Edobashi, Tsu, Mie, 514-8507, Japan. kakuya@med.mie-u.ac.jp.ORCID http://orcid.org/0000-0003-4402-6846
Sachio MizutaniDepartment of Radiology, Matsusaka Municipal Hospital, Matsusaka, Japan.
Akane HamaguchiDepartment of Radiology, Matsusaka Municipal Hospital, Matsusaka, Japan.
Ryosuke KisouDepartment of Radiology, Matsusaka Municipal Hospital, Matsusaka, Japan.
Kenji SasakiDepartment of Radiology, Matsusaka Municipal Hospital, Matsusaka, Japan.
Yuto FunakiDepartment of Radiology, Matsusaka Municipal Hospital, Matsusaka, Japan.
Kotaro IioDepartment of Cardiology, Matsusaka Municipal Hospital, Matsusaka, Japan.
Kazuhide IchikawaDepartment of Cardiology, Matsusaka Municipal Hospital, Matsusaka, Japan.
Daisuke IzumiDepartment of Cardiology, Matsusaka Municipal Hospital, Matsusaka, Japan.
Shiko OkabeDepartment of Radiology, Mie University Graduate School of Medicine, 2-174 Edobashi, Tsu, Mie, 514-8507, Japan.
Motonori NagataDepartment of Radiology, Mie University Graduate School of Medicine, 2-174 Edobashi, Tsu, Mie, 514-8507, Japan.
Hajime SakumaDepartment of Radiology, Mie University Graduate School of Medicine, 2-174 Edobashi, Tsu, Mie, 514-8507, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeMyocardial computed tomography (CT) late enhancement (LE) allows assessment of myocardial scarring. Super-resolution deep learning image reconstruction (SR-DLR) trained on data acquired from ultra-high-resolution CT may improve image quality for CT-LE. Therefore, this study investigated image noise and image quality with SR-DLR compared with conventional DLR (C-DLR) and hybrid iterative reconstruction (hybrid IR). METHODS AND

methodsWe retrospectively analyzed 30 patients who underwent CT-LE using 320-row CT. The CT protocol comprised stress dynamic CT perfusion, coronary CT angiography, and CT-LE. CT-LE images were reconstructed using three different algorithms: SR-DLR, C-DLR, and hybrid IR. Image noise, signal-to-noise ratio (SNR), contrast-to-noise ratio (CNR), and qualitative image quality scores are in terms of noise reduction, sharpness, visibility of scar and myocardial boarder, and overall image quality. Inter-observer differences in myocardial scar sizing in CT-LE by the three algorithms were also compared.

resultsSR-DLR significantly decreased image noise by 35% compared to C-DLR (median 6.2 HU, interquartile range [IQR] 5.6-7.2 HU vs 9.6 HU, IQR 8.4-10.7 HU; p < 0.001) and by 37% compared to hybrid IR (9.8 HU, IQR 8.5-12.0 HU; p < 0.001). SNR and CNR of CT-LE reconstructed using SR-DLR were significantly higher than with C-DLR (both p < 0.001) and hybrid IR (both p < 0.05). All qualitative image quality scores were higher with SR-DLR than those with C-DLR and hybrid IR (all p < 0.001). The inter-observer differences in scar sizing were reduced with SR-DLR and C-DLR compared with hybrid IR (both p = 0.02).

conclusionSR-DLR reduces image noise and improves image quality of myocardial CT-LE compared with C-DLR and hybrid IR techniques and improves inter-observer reproducibility of scar sizing compared to hybrid IR. The SR-DLR approach has the potential to improve the assessment of myocardial scar by CT late enhancement.

Indexed as

Deep LearningHeartRadiographic Image EnhancementRadiographic Image Interpretation, Computer-AssistedTomography, X-Ray ComputedAgedAlgorithmsContrast MediaCoronary AngiographyFemaleHumansMaleMiddle AgedRetrospective StudiesSignal-To-Noise RatioContrast MediaCardiac imaging techniqueComputed tomography angiographyDeep learningImage reconstructionMyocardial infarction

Identifiers

PMID40072715
PMCPMC12204928

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.