Evidence map›Paper›PMID 40072673›Full record

ArticleInflammopharmacology2025

Unveiling the neuroprotective potential of Ipomoea carnea ethanol extract via the modulation of tau and β-secretase pathways in AlCl

Walaa A El-Kashak, Ahmed F Essa, Mohamed F Abdelhameed, Yasmine H Ahmed, Asmaa S Abd Elkarim, Mai M Elghonemy, Bassant M M Ibrahim, Ahmed H Gaara, Tahia K Mohamed, Abdelsamed I Elshamy

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Inflammopharmacology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Walaa A El-KashakChemistry of Natural Compounds Department, National Research Centre, 33 El Bohouth St, Dokki, Giza, 12622, Egypt.
Ahmed F EssaChemistry of Natural Compounds Department, National Research Centre, 33 El Bohouth St, Dokki, Giza, 12622, Egypt.
Mohamed F AbdelhameedPharmacology Department, National Research Centre, Dokki, 12622, Giza, Egypt.
Yasmine H AhmedDepartment of Cytology and Histology, Faculty of Veterinary Medicine, Cairo University, Giza, 12211, Egypt.
Asmaa S Abd ElkarimChemistry of Tanning Materials and Leather Technology Department, National Research Centre, 33 El Bohouth St., Dokki, 12622, Giza, Egypt.
Mai M ElghonemyChemistry of Natural Compounds Department, National Research Centre, 33 El Bohouth St, Dokki, Giza, 12622, Egypt.
Bassant M M IbrahimPharmacology Department, National Research Centre, Dokki, 12622, Giza, Egypt.
Ahmed H GaaraChemistry of Natural Compounds Department, National Research Centre, 33 El Bohouth St, Dokki, Giza, 12622, Egypt.
Tahia K MohamedChemistry of Natural Compounds Department, National Research Centre, 33 El Bohouth St, Dokki, Giza, 12622, Egypt.
Abdelsamed I ElshamyChemistry of Natural Compounds Department, National Research Centre, 33 El Bohouth St, Dokki, Giza, 12622, Egypt. elshamynrc@yahoo.com.ORCID http://orcid.org/0000-0003-3302-3623

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Alzheimer's disease (AD) is a widespread condition that affects adults and the community considerably. The causes are yet unknown, except from advanced age and genetic predisposition. Natural products provided advantageous advantages for managing AD due to their efficacy, safety, and accessibility. The memory boosting effects of chemically characterized Ipomoea carnea ethanol extract (IPC-EtOH) on behavioral, biochemical, histological, and molecular levels against cognitive impairment induced by AlCl

Indexed as

Amyloid Precursor Protein SecretasesMemory DisordersNeuroprotective AgentsPlant Extractstau ProteinsAluminum ChlorideAnimalsDisease Models, AnimalEthanolMaleMaze LearningOxidative StressPhytochemicalsRatsRats, WistarAluminum ChlorideAmyloid Precursor Protein SecretasesEthanolNeuroprotective AgentsPhytochemicalsPlant Extractstau ProteinsAlCl3Alzheimer’s diseaseIpomoea carneaTauβ-secretase pathway

Identifiers

PMID40072673
PMCPMC11991951

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.