Evidence map›Paper›PMID 40072667›Full record

ReviewDaru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences2025

Vancomycin- induced leukocytoclastic vasculitis in a patient with end-stage renal disease: a case report and literature review.

Maryam S Fakhri B, Ghazal Roostaei, Shila Aghayani, Mohammad Hossein Shojamoradi, Behnoud Vesali, Niloofar Khoshnam Rad

Abstract readCase ReportsReview
In one paragraph

Review in Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Maryam S Fakhri BDepartment of Internal Medicine, Imam Khomeini, Hospital Complex, Tehran University of Medical Science, Tehran, Iran.
Ghazal RoostaeiSchool of Medicine, Iran University of Medical Sciences, Tehran, Iran.
Shila AghayaniDepartment of Rheumatology, Imam Khomeini Hospital Complex, Tehran University of Medical Science, Tehran, Iran.
Mohammad Hossein ShojamoradiNephrology Research Center, University of Medical Sciences, TehranTehran, Iran.
Behnoud VesaliCancer Institute of Tehran Medical University, Tehran, Iran.
Niloofar Khoshnam RadThoracic Research Center, Imam Khomeini, Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran. kh.niloofar@yahoo.com.ORCID http://orcid.org/0000-0001-6700-3570

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionLeukocytoclastic vasculitis (LCV) is a small-vessel inflammatory condition that can rarely occur as an adverse drug reaction (ADR). Vancomycin-induced LCV is an uncommon but potentially serious complication, particularly in patients with pre-existing renal impairment. REASON FOR THE REPORT: This case report describes a patient with end-stage renal disease (ESRD) who developed LCV following vancomycin therapy for a catheter-related infection. The report emphasizes the diagnostic challenges and the importance of prompt and appropriate management of this ADR. A 53-year-old male with ESRD developed skin lesions and systemic symptoms after receiving vancomycin for catheter-related infection. The diagnosis of LCV was confirmed through a skin biopsy. Discontinuation of vancomycin with initiation of mycophenolate mofetil and prednisolone resulted in significant improvement in the patient's condition. OUTCOME: The presented case underlines the recognition of vancomycin-induced LCV, especially in the vulnerable population of patients with ESRD. It emphasizes the need for a high degree of suspicion of drug-related adverse events and early diagnosis and management to achieve good outcomes. CLINICAL TRIAL NUMBER: Not applicable.

Indexed as

Anti-Bacterial AgentsKidney Failure, ChronicVancomycinVasculitis, Leukocytoclastic, CutaneousCatheter-Related InfectionsHumansMaleMiddle AgedPrednisoloneAnti-Bacterial AgentsPrednisoloneVancomycinEnd-Stage Renal DiseaseLeukocytoclastic VasculitisVancomycin

Identifiers

PMID40072667
PMCPMC11904013

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.