Evidence map›Paper›PMID 40072619›Full record

ArticleHernia : the journal of hernias and abdominal wall surgery2025

Outcomes of quadratus lumborum blocks for pain control after open abdominal wall reconstruction: a single institution retrospective analysis.

Sarah Budney, Eric Middleton, Kyle Kleppe, Matthew Mancini, Gregory Mancini, Melissa Phillips, Catherine McKnight, John Griepentrog, Aldo Fafaj, Kaela E Blake

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Article in Hernia : the journal of hernias and abdominal wall surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

10 authors.

Sarah BudneyUniversity of Tennessee Graduate School of Medicine, Knoxville, TN,, 37920, USA. sarahmbudney@gmail.com.ORCID 0000-0003-1157-941X
Eric MiddletonUniversity of Tennessee Graduate School of Medicine, Knoxville, TN,, 37920, USA.
Kyle KleppeUniversity of Tennessee Graduate School of Medicine, Knoxville, TN,, 37920, USA.
Matthew ManciniUniversity of Tennessee Graduate School of Medicine, Knoxville, TN,, 37920, USA.
Gregory ManciniUniversity of Tennessee Graduate School of Medicine, Knoxville, TN,, 37920, USA.
Melissa PhillipsUniversity of Tennessee Graduate School of Medicine, Knoxville, TN,, 37920, USA.
Catherine McKnightUniversity of Tennessee Graduate School of Medicine, Knoxville, TN,, 37920, USA.
John GriepentrogUniversity of Tennessee Graduate School of Medicine, Knoxville, TN,, 37920, USA.
Aldo FafajUniversity of Tennessee Graduate School of Medicine, Knoxville, TN,, 37920, USA.
Kaela E BlakeUniversity of Tennessee Graduate School of Medicine, Knoxville, TN,, 37920, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionAbdominal wall reconstruction (AWR) is associated with significant post-operative pain for which there is no standardized treatment regimen. Quadratus lumborum (QL) blocks have not been studied in open ventral hernia repair. This study reviews our institution's experience with QL blocks in open AWR.

methodsA retrospective review from October 2022 to October 2024 was completed. Patients undergoing elective, open abdominal wall reconstruction who received pre-operative QL blocks were included. Variables analyzed included patient demographics, comorbidities, operative technique, mesh type, daily opioid consumption reported as morphine milliequivalents (MMEs), and length of stay. The primary outcome was MMEs consumed in the first 24 h after surgery.

resultsThere were 102 patients included in the study. The first 24-hour median opioid MME consumption was 8 (IQR 0-67.5). The median MMEs peaked on day 2 at 47 (IQR 30-114) and then trended down each day. The median length of stay was 4.3 days (IQR 4.1-5.9). There were no complications related to the QL block procedure.

conclusionThis is the first study to report on post-operative opioid consumption in patients receiving a quadratus lumborum block prior to open ventral hernia repair. We found patients consumed minimal MMEs in the first 24 h after surgery suggesting that QL blocks may provide analgesic benefit in abdominal wall reconstruction.

Indexed as

Abdominal WallHernia, VentralHerniorrhaphyNerve BlockPain ManagementPostoperative PainAbdominal MusclesAgedAnalgesics, OpioidFemaleHumansLength of StayMaleMiddle AgedRetrospective StudiesTreatment OutcomeAnalgesics, OpioidAbdominal wall reconstructionOpioidPainQuadratus lumborum blockTransversus abdominis releaseVentral hernia repair

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.