Evidence map›Paper›PMID 40072580›Full record

ArticleArchives of women's mental health2025

Network analysis of PTSD symptoms following childbirth and comorbid conditions among women with sexual trauma history.

Gabriella E Hamlett, Shaan F McGhie, Gabriella Dishy, Sabrina J Chan, Richard J McNally, Sharon Dekel

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In one paragraph

Article in Archives of women's mental health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Gabriella E HamlettDepartment of Psychology, Harvard University, 33 Kirkland Street, Cambridge, MA, 02138, USA.ORCID 0000-0003-3764-2966
Shaan F McGhieDepartment of Psychology, Harvard University, 33 Kirkland Street, Cambridge, MA, 02138, USA.ORCID 0000-0002-9337-8226
Gabriella DishyDepartment of Psychiatry, Massachusetts General Hospital, B62 13th Street, Charlestown, MA, 02129, USA.ORCID 0000-0001-5852-9693
Sabrina J ChanDepartment of Psychiatry, Massachusetts General Hospital, B62 13th Street, Charlestown, MA, 02129, USA.ORCID 0000-0002-4557-2972
Richard J McNallyDepartment of Psychology, Harvard University, 33 Kirkland Street, Cambridge, MA, 02138, USA.ORCID 0000-0002-5228-8777
Sharon DekelDepartment of Psychiatry, Massachusetts General Hospital, B62 13th Street, Charlestown, MA, 02129, USA. sdekel@mgh.harvard.edu.ORCID 0000-0003-4528-0993

Funding

Defining postpartum PTSD and its implications for maternal wellness and child developmentR01HD108619 · NICHD · MASSACHUSETTS GENERAL HOSPITAL · PI Sharon Dekel · 2022 to 2026
$3.7M
Neural underpinnings of postpartum adaptation following traumatic delivery and implications for infant developmentR21HD100817 · NICHD · MASSACHUSETTS GENERAL HOSPITAL · PI DEKEL, SHARON · 2020 to 2021
$574k
The effects of expressive writing following traumatic childbirthR21HD109546 · NICHD · MASSACHUSETTS GENERAL HOSPITAL · PI DEKEL, SHARON · 2023 to 2024
$462k
Eunice Kennedy Shriver National Institute of Child Health and Human Development R01HD108619Eunice Kennedy Shriver National Institute of Child Health and Human Development R21HD100817Eunice Kennedy Shriver National Institute of Child Health and Human Development R21HD109546NICHD NIH HHS R01 HD108619NICHD NIH HHS R21 HD100817NICHD NIH HHS R21 HD109546
6 · The paper itself

Abstract

purposeWomen with a history of sexual trauma (ST) have heightened risk for postpartum psychopathology. Although ST increases risk for traumatic delivery and maternal psychopathology, knowledge of the functional connections among various psychiatric symptoms and complicated delivery remains limited.

methodsWe used regularized partial correlation networks to examine connections between symptoms of childbirth-related PTSD (CB-PTSD), depression, anxiety, somatization, obsessive-compulsive disorder, and complicated delivery (e.g., presence of obstetric complications, preterm birth, advanced maternal age) in 1,916 postpartum women. We compared networks of women with and without a history of sexual trauma (n

resultsComplicated delivery in both groups connected with three CB-PTSD clusters: reexperiencing, avoidance, and negative alterations in cognition and mood. Network comparison tests revealed a significant difference in global strength invariance, but not network invariance. ST network CB-PTSD nodes were significantly more strongly interconnected as compared to those with no ST (NST). Conversely, stronger connections in the NST network were Mood with Anxiety and Avoidance with Somatic symptoms.

conclusionThe ST group's stronger PTSD symptom coactivation may reflect differences in risk for the emergence of CB-PTSD for women with a history of ST.

Indexed as

ParturitionSexual TraumaStress Disorders, Post-TraumaticAdultAnxietyComorbidityDepressionFemaleHumansObsessive-Compulsive DisorderPostpartum PeriodPregnancyYoung AdultNetwork analysisPerinatalPostpartum PTSDSexual trauma

Identifiers

PMID40072580
PMCPMC12353851

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