ArticleEuropean archives of psychiatry and clinical neuroscience2026
Suboptimal antidepressant use among inpatients and outpatients with symptoms of depression: a cross-sectional analysis of the POKAL core data set.
Article in European archives of psychiatry and clinical neuroscience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- PACIC: patient activation and problem solving not related to age in patients with depressive symptoms.European archives of psychiatry and clinical neuroscience · 2026Article
- Clinical behavior toward outpatients with major depressive disorder based on guideline education for psychiatrists.PCN reports : psychiatry and clinical neurosciences · 2025Article
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Authors and funding
24 authors.
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Abstract
We present a cross-sectional analysis of 1391 outpatients and 280 inpatients participating in subprojects of the Research Training Group POKAL, of whom 1609 had a PHQ-9 score ≥ 5 and 62 reported depression with antidepressant use. Antidepressant use was lower among outpatients than inpatients (28.5% vs. 82.5%), with higher levels of SSRI monotherapy (44.1% vs. 25.5%). Of antidepressant users, 80.1% had potentially inadequate treatment response, 21.7% high-risk use and of those with severe symptoms, 42.1% were potentially undertreated. Key risk factors were higher anxiety levels (for inadequate treatment response) and polypharmacy (for high-risk use), while previous depressive episode was protective against potential undertreatment.
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