Evidence map›Paper›PMID 40072382›Full record

ArticleAnnals of emergency medicine2025

Outcomes of Older Adults With Delirium Discharged From the Emergency Department.

Annelise S Howick, Piayeng Thao, Kayla P Carpenter, Madeline A Boie, Ian Ward A Maia, Aidan F Mullan, Susan M Bower, Allyson K Palmer, Christopher R Carpenter, Shan W Liu and 2 more

Abstract read
In one paragraph

Article in Annals of emergency medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Beyond Triage: Cognitive Profiles and ED-To-Inpatient Costs and Resource Pathways in Older Adults.Academic emergency medicine : official journal of the Society for Academic Emergency Medicine · 2026
    Article
  6. Observational
  7. Observational
  8. Article
  9. Article
  10. Article
  11. Observational
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Annelise S HowickDepartment of Emergency Medicine, Mayo Clinic, Rochester, MN.
Piayeng ThaoDepartment of Emergency Medicine, Mayo Clinic, Rochester, MN.
Kayla P CarpenterDepartment of Emergency Medicine, Mayo Clinic, Rochester, MN.
Madeline A BoieDepartment of Emergency Medicine, Mayo Clinic, Rochester, MN.
Ian Ward A MaiaDepartment of Emergency Medicine, Mayo Clinic, Rochester, MN.
Aidan F MullanDepartment of Quantitative Health Sciences, Mayo Clinic, Rochester, MN.
Susan M BowerDepartment of Emergency Medicine, Mayo Clinic, Rochester, MN; Department of Nursing, Mayo Clinic, Rochester, MN.
Allyson K PalmerDivision of Hospital Internal Medicine, Department of Medicine, Mayo Clinic, Rochester, MN; Robert and Arlene Kogod Center on Aging, Mayo Clinic, Rochester, MN; Robert D. and Patricia E. Kern Center for the Science of Health Care Delivery, Mayo Clinic, Rochester, MN.
Christopher R CarpenterDepartment of Emergency Medicine, Mayo Clinic, Rochester, MN; Robert and Arlene Kogod Center on Aging, Mayo Clinic, Rochester, MN.
Shan W LiuDepartment of Emergency Medicine, Massachusetts General Hospital, Boston, MA.
Molly M JefferyDepartment of Emergency Medicine, Mayo Clinic, Rochester, MN; Robert D. and Patricia E. Kern Center for the Science of Health Care Delivery, Mayo Clinic, Rochester, MN.
Fernanda BellolioDepartment of Emergency Medicine, Mayo Clinic, Rochester, MN; Robert and Arlene Kogod Center on Aging, Mayo Clinic, Rochester, MN. Electronic address: Bellolio.fernanda@mayo.edu.

Funding

Mayo Clinic Center for Clinical and Translational Science (CCaTS UL1 Supplement - Dr. Timothy Curry)UL1TR002377 · NCATS · MAYO CLINIC ROCHESTER · PI VESNA D GAROVIC · 2017 to 2026
$78.4M
NCATS NIH HHS UL1 TR002377
6 · The paper itself

Abstract

STUDY

objectiveTo compare 30-day mortality and return emergency department (ED) visits among older adults with delirium who are discharged home with those discharged home without delirium and those who are admitted to the hospital with and without delirium.

methodsAdults aged 75 and older years were assessed for delirium using the Delirium Triage Screen followed by the Brief Confusion Assessment Method. We evaluated outcomes including return visits and 30-day mortality. Models were adjusted by age, sex, dementia, Modified Early Warning Score, and ED length of stay and summarized with adjusted relative risk (aRR) and 95% confidence intervals (CIs).

resultsThe study included 22,940 visits. Among them, 202 (0.9%) delirium-positive patients were discharged, and 730 (3.2%) were admitted to the hospital to non-ICU and nonmonitored beds. Discharged patients with delirium had higher 30-day mortality (aRR 2.86, 95% CI 2.04 to 4.00) and were more likely to return to the ED within 30 days (aRR 1.52, 95% CI 1.43 to 1.61) compared with those discharged without delirium. Discharged delirium-positive patients were more likely to return to the ED within 30 days than hospitalized delirium-positive patients (aRR 1.92, 95% CI 1.41 to 1.92), though they experienced lower 30-day mortality (aRR 0.67, 95% CI 0.47 to 0.93). Age, sex, Modified Early Warning Score, dementia, and length of stay were not associated with mortality or ED return.

conclusionPatients discharged with delirium experienced a 3-fold increase in mortality within 30 days compared with those discharged without delirium. These findings suggest a need for more precise discharge criteria and enhanced follow-up care for delirious patients to improve safety. Implementing structured screening and tailored postdischarge support could reduce adverse outcomes in this population.

Indexed as

DeliriumEmergency Service, HospitalPatient DischargePatient ReadmissionAgedAged, 80 and overFemaleHumansLength of StayMaleDementiaFrailtyGeriatrics, deliriumMortalityOlder adult

Identifiers

PMID40072382
PMCPMC12353625

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.