Evidence map›Paper›PMID 40072270›Full record

ArticleJournal of veterinary internal medicine

Iatrogenic Primary Hypothyroidism Associated With Sulfamethoxazole-Trimethoprim Treatment of Nocardiosis in a Cat.

Deborah Alexander, Gustavo C Cobucci, Cassia C da Motta, Gabriela de C Cid, Lana S Belizzi, Amanda C de Jesus, Heloisa J Souza, Mark E Peterson

Abstract readCase Reports
In one paragraph

Article in Journal of veterinary internal medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Spontaneous adult-onset primary hypothyroidism in 17 cats.Journal of feline medicine and surgery · 2026
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Deborah AlexanderVida Felina Veterinary Clinic, Rio de Janeiro, Rio de Janeiro, Brazil.ORCID https://orcid.org/0000-0003-0292-2976
Gustavo C CobucciGammaVet, Rio de Janeiro, Rio de Janeiro, Brazil.ORCID https://orcid.org/0000-0002-0997-5221
Cassia C da MottaTECSA Laboratory, Rio de Janeiro, Rio de Janeiro, Brazil.ORCID https://orcid.org/0009-0004-6643-1054
Gabriela de C CidUniversidade Federal Rural do Rio de Janeiro, Seropédica, Rio de Janeiro, Brazil.ORCID https://orcid.org/0000-0002-8078-9093
Lana S BelizziVida Felina Veterinary Clinic, Rio de Janeiro, Rio de Janeiro, Brazil.ORCID https://orcid.org/0009-0001-7001-1827
Amanda C de JesusVida Felina Veterinary Clinic, Rio de Janeiro, Rio de Janeiro, Brazil.ORCID https://orcid.org/0000-0003-2662-1676
Heloisa J SouzaUniversidade Federal Rural do Rio de Janeiro, Seropédica, Rio de Janeiro, Brazil.ORCID https://orcid.org/0000-0002-4077-5981
Mark E PetersonAnimal Endocrine Clinic, New York, New York, USA.ORCID https://orcid.org/0000-0002-3016-1855

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 9-year-old mixed breed cat with a history of recurrent ulcerated skin lesions was diagnosed with nocardiosis. Three months after initiating potentiated sulfonamide treatment, the cat developed goitrous hypothyroidism, characterized by palpable enlargement of both thyroid lobes, low serum concentrations of total thyroxine (T4) and free thyroxine (fT4), and high serum thyroid-stimulating hormone (TSH) concentration. Thyroid scintigraphy identified symmetrical enlargement of both thyroid lobes, with increased radionuclide (

Indexed as

Anti-Bacterial AgentsCat DiseasesHypothyroidismNocardia InfectionsTrimethoprim, Sulfamethoxazole Drug CombinationAnimalsCatsFemaleIatrogenic DiseaseNocardiaAnti-Bacterial AgentsTrimethoprim, Sulfamethoxazole Drug Combinationfelinegoitrous hypothyroidismnocardiascintigraphythyroid glandthyroid‐stimulating hormone

Identifiers

PMID40072270
PMCPMC11898863

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.