Evidence map›Paper›PMID 40072060›Full record

Trial reportCells2025

One Month of Brief Weekly Magnetic Field Therapy Enhances the Anticancer Potential of Female Human Sera: Randomized Double-Blind Pilot Study.

Jan Nikolas Iversen, Yee Kit Tai, Jasmine Lye Yee Yap, Rafhanah Banu Binte Abdul Razar, Viresh Krishnan Sukumar, Kwan Yu Wu, Melissa Gaik-Ming Ooi, Marek Kukumberg, Sabrina Adam, Abdul Jalil Rufaihah and 1 more

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Cells, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Jan Nikolas IversenDepartment of Surgery, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 119228, Singapore.ORCID 0000-0001-5900-2033
Yee Kit TaiDepartment of Surgery, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 119228, Singapore.
Jasmine Lye Yee YapDepartment of Surgery, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 119228, Singapore.
Rafhanah Banu Binte Abdul RazarDepartment of Surgery, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 119228, Singapore.
Viresh Krishnan SukumarDepartment of Surgery, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 119228, Singapore.ORCID 0009-0006-9715-172X
Kwan Yu WuDepartment of Surgery, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 119228, Singapore.ORCID 0009-0004-9942-239X
Melissa Gaik-Ming OoiNUS Centre for Cancer Research, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117599, Singapore.ORCID 0000-0002-7392-0655
Marek KukumbergHealthy Longevity Translational Research Programme, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 119228, Singapore.
Sabrina AdamHealthy Longevity Translational Research Programme, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 119228, Singapore.
Abdul Jalil RufaihahDepartment of Surgery, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 119228, Singapore.
Alfredo Franco-ObregónDepartment of Surgery, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 119228, Singapore.ORCID 0000-0002-2514-1083

Funding

Healthy Longevity Catalyst Award (NMRC) A-0001337-00-00Pulsing Magnetic Field Therapy Research Fund E-551-00-0004-01Singapore Therapeutic Development Review (A*STAR) A08001939-00-00
6 · The paper itself

Abstract

Preclinical studies have shown that the blood from female mice exposed weekly to magnetic fields inhibited breast cancer growth. This double-blind randomized controlled trial investigated whether analogous magnetic therapy could produce similar anticancer sera from human subjects. Twenty-six healthy adult females (ages 30-45) were assigned to either a magnetic therapy group, receiving twice weekly 1 mT magnetic exposures (10 min/session) for 4 weeks, or a control group, who underwent identical sham exposure. Blood sera were evaluated for their capacity to modulate breast cancer-related cellular responses and epithelial-mesenchymal transition. The sera from the magnetic therapy group subjects exhibited significant anticancer effects that were strongest one month after the last magnetic exposure, whereas the sera from unexposed females or unexposed or exposed males showed no effect. Female sera from the magnetic therapy group (

Indexed as

Breast NeoplasmsMagnetic FieldsMagnetic Field TherapyAdultCell MovementCell ProliferationDouble-Blind MethodEpithelial-Mesenchymal TransitionFemaleHumansMaleMiddle AgedPilot Projectsangiogenesisbreast cancerepithelial–mesenchymal transitionmetastasisperipheral artery diseasesoluble biomarkers

Identifiers

PMID40072060
PMCPMC11899448

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.