Evidence map›Paper›PMID 40071958›Full record

ArticleWomen's health (London, England)

Examining acquired brain injury-associated symptoms and fluid-based biomarkers in females surviving intimate partner violence: An observational pilot study protocol.

Michelle Patch, Allison Jacobi-Dorbeck, Tamar Rodney, Gabor Kelen, Jacquelyn C Campbell, Leah H Rubin, Chelsea Wagner, Nancy Perrin, Jessica Gill

Abstract readClinical Trial Protocol
In one paragraph

Article in Women's health (London, England). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Michelle PatchJohns Hopkins University School of Nursing, Baltimore, MD, USA.ORCID 0000-0003-3639-6003
Allison Jacobi-DorbeckDepartment of Emergency Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Tamar RodneyJohns Hopkins University School of Nursing, Baltimore, MD, USA.
Gabor KelenJohns Hopkins University School of Medicine, Baltimore, MD, USA.
Jacquelyn C CampbellJohns Hopkins University School of Nursing, Baltimore, MD, USA.
Leah H RubinJohns Hopkins University School of Medicine, Baltimore, MD, USA.
Chelsea WagnerGill Clinical Translational Laboratory, Johns Hopkins University School of Nursing, Baltimore, MD, USA.
Nancy PerrinJohns Hopkins University School of Nursing, Baltimore, MD, USA.
Jessica GillJohns Hopkins University Schools of Nursing and Medicine, Baltimore, MD, USA.

Funding

The Johns Hopkins Clinical Research Scholars in Women's Health (BIRCWH)K12AR084229 · NIAMS · JOHNS HOPKINS UNIVERSITY · PI Daniel Ernest Ford, NANCY E GLASS · 2023 to 2026
$2.7M
NIAMS NIH HHS K12 AR084229
6 · The paper itself

Abstract

backgroundAcquired brain injury (ABI), including traumatic brain injury and hypoxic/anoxic injury, presents significant public health concerns; however, existing literature has focused primarily on male populations, such as military personnel and contact sports participants. Sex-related differences in ABI outcomes necessitate focused research due to potential heightened risk and distinct physiological responses among females.

objectivesThis pilot study aims to explore fluid-based biomarkers for neurological injury and inflammation in females experiencing intimate partner violence (IPV)-related assaults to the head, neck, or face. It seeks to assess the feasibility and acceptability of non-invasive sweat patch collection for biomarker analysis and its association with post-injury symptoms.

designThis study will be a prospective longitudinal observational pilot study involving approximately 50 participants recruited from two mid-Atlantic-based hospital emergency departments. METHODS AND ANALYSIS: Participants will undergo clinical interviews, provide blood and sweat samples, and complete questionnaires assessing ABI history, IPV-related symptoms, cognitive function, psychological well-being, and sweat patch acceptability, across three study visits. Screening procedures will identify eligible participants, followed by consent procedures, biosample collection, brain injury and IPV history survey administration, symptom and cognitive function instrument administration, and acute medical record data collection. Analyses will include random effects regression, product moment correlations, and descriptive statistics. ETHICS: Participants will be informed about the study's purpose, procedures, and potential risks before providing consent. Compensation will be provided for participation, with withdrawal options available. Ethical considerations include ensuring participant confidentiality and addressing psychological disorders beyond exclusion criteria. DISCUSSION: Understanding fluid-based biomarkers in IPV-related ABI can inform interdisciplinary interventions and precision care models. Findings may facilitate early detection, treatment, and safety planning for affected females, emphasizing the importance of tailored, accessible care for this vulnerable population. Future research should focus on translating these findings into evidence-based practice to improve outcomes for women with ABI, particularly those resulting from IPV.

Indexed as

BiomarkersBrain InjuriesIntimate Partner ViolenceAdultFemaleHumansLongitudinal StudiesObservational Studies as TopicPilot ProjectsProspective StudiesBiomarkersbiomarkersbrain injuryintimate partner violencewomen’s health

Identifiers

PMID40071958
PMCPMC11905024

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.