Evidence map›Paper›PMID 40071953›Full record

ArticleInfection and immunity2025

Polyphosphatases have a polyphosphate-independent influence on the virulence of

Kabir Bhalla, Eddy Sánchez León-Hing, Yu-Hsuan Huang, Victoria French, Guanggan Hu, Jen Wang, Matthias Kretschmer, Xianya Qu, Raphaell Moreira, E Johan Foster and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Infection and immunity, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Inorganic Polyphosphate and Human Diseases.Progress in molecular and subcellular biology · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Kabir BhallaMichael Smith Laboratories, University of British Columbia, Vancouver, British Columbia, Canada.
Eddy Sánchez León-HingMichael Smith Laboratories, University of British Columbia, Vancouver, British Columbia, Canada.
Yu-Hsuan HuangDepartment of Microbiology and Immunology, University of British Columbia, Vancouver, British Columbia, Canada.
Victoria FrenchDepartment of Chemical and Biological Engineering, BioProducts Institute, University of British Columbia, Vancouver, British Columbia, Canada.
Guanggan HuMichael Smith Laboratories, University of British Columbia, Vancouver, British Columbia, Canada.
Jen WangMichael Smith Laboratories, University of British Columbia, Vancouver, British Columbia, Canada.
Matthias KretschmerMichael Smith Laboratories, University of British Columbia, Vancouver, British Columbia, Canada.
Xianya QuMichael Smith Laboratories, University of British Columbia, Vancouver, British Columbia, Canada.
Raphaell MoreiraDepartment of Chemical and Biological Engineering, BioProducts Institute, University of British Columbia, Vancouver, British Columbia, Canada.
E Johan FosterDepartment of Chemical and Biological Engineering, BioProducts Institute, University of British Columbia, Vancouver, British Columbia, Canada.
Pauline JohnsonDepartment of Microbiology and Immunology, University of British Columbia, Vancouver, British Columbia, Canada.
James W KronstadMichael Smith Laboratories, University of British Columbia, Vancouver, British Columbia, Canada.ORCID 0000-0003-4240-6976

Funding

Comparative and functional genomics of C. neoformansR01AI053721 · NIAID · UNIVERSITY OF BRITISH COLUMBIA · PI KRONSTAD, JAMES W · 2003 to 2024
$5.4M
Canadian Foundation for Innovation 022176Canadian Government | Canadian Institutes of Health Research (CIHR) PJT-166043Canadian Government | Natural Sciences and Engineering Research Council of Canada (NSERC) RGPIN-2021-03172HHS | NIH | National Institute of Allergy and Infectious Diseases (NIAID) R01AI053721Natural Sciences and Engineering Research Council of Canada Canfor Industrial Research Chair in Advanced Bioproducts 553449-19NIAID NIH HHS R01 AI053721
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

CryptococcosisCryptococcus neoformansFungal ProteinsPolyphosphatesAnimalsDisease Models, AnimalFemaleMiceMutationVirulenceVirulence FactorsFungal ProteinsPolyphosphatesVirulence Factorscapsulefungal pathogenesisimmunitymelaninmitochondrial metabolismpolyphosphate

Identifiers

PMID40071953
PMCPMC11977306

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.