Evidence map›Paper›PMID 40071948›Full record

ArticlemBio2025

SENP1-SIRT3 axis mediates glycolytic reprogramming to suppress inflammation during

Yan Xiong, Yongliang Du, Feng Lin, Beibei Fu, Dong Guo, Zhou Sha, Rong Tian, Rui Yao, Lulu Wang, Zixuan Cong and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in mBio, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Yan Xiong *School of Life Sciences, Chongqing University, Chongqing, China.
Yongliang Du *School of Life Sciences, Chongqing University, Chongqing, China.
Feng Lin *School of Life Sciences, Chongqing University, Chongqing, China.
Beibei FuSchool of Life Sciences, Chongqing University, Chongqing, China.
Dong GuoSchool of Life Sciences, Chongqing University, Chongqing, China.
Zhou ShaSchool of Life Sciences, Chongqing University, Chongqing, China.
Rong TianDepartment of Pathology, Chongqing Hygeia Hospital, Chongqing, China.
Rui YaoDepartment of Pathology, Chongqing Hygeia Hospital, Chongqing, China.
Lulu WangSchool of Life Sciences, Chongqing University, Chongqing, China.
Zixuan CongSchool of Life Sciences, Chongqing University, Chongqing, China.
Bohao LiSchool of Life Sciences, Chongqing University, Chongqing, China.
Xiaoyuan LinDepartment of Clinical Microbiology and Immunology, College of Pharmacy and Medical Laboratory, Army Medical University (Third Military Medical University), Chongqing, China.ORCID 0000-0002-3361-0126
Haibo WuSchool of Life Sciences, Chongqing University, Chongqing, China.ORCID 0000-0002-5961-2947

Funding

National Natural Science Foundation of China No. 92369115, 82422048Natural Science Foundation of Chongqing, China；Chongqing Talents: Exceptional Young Talents Project No. CSTB2023NSCQMSX0402；No. cstc2021ycjh-bgzxm0099
6 · The paper itself

Abstract

IMPORTANCE: Sentrin-specific protease 1 (SENP1)-sirtuin 3 (SIRT3) has never been reported in the regulation of bacteria-induced inflammation. Our study demonstrated that SENP1 acted as a protective factor against

Indexed as

Cysteine EndopeptidasesGlycolysisInflammationListeria monocytogenesListeriosisSirtuin 3AnimalsHumansMiceMice, Inbred C57BLMitochondriaSignal TransductionCysteine EndopeptidasesSenp1 protein, mouseSirt3 protein, mouseSirtuin 3glycolysisListeria monocytogenesPKM2SENP1-SIRT3 axisSUMO

Identifiers

PMID40071948
PMCPMC11980586

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.