Evidence map›Paper›PMID 40071918›Full record

ArticleApplied and environmental microbiology2025

The impact of anthropogenic activities on antimicrobial and heavy metal resistance in aquatic environments.

Md Javed Foysal, Brett A Neilan, Verlaine Timms

Abstract read
In one paragraph

Article in Applied and environmental microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Md Javed FoysalSchool of Environmental and Life Sciences, The University of Newcastle, Callaghan, New South Wales, Australia.ORCID 0000-0002-2064-8897
Brett A NeilanSchool of Environmental and Life Sciences, The University of Newcastle, Callaghan, New South Wales, Australia.ORCID 0000-0001-6113-772X
Verlaine TimmsSchool of Environmental and Life Sciences, The University of Newcastle, Callaghan, New South Wales, Australia.ORCID 0000-0002-3883-4428

Funding

Australian Research Council Centre of Excellence in Synthetic Biology CE200100029
6 · The paper itself

Abstract

This study investigated the prevalence and co-occurrence of antimicrobial (AMR) and metal resistance (MR) in aquatic environments with different human impacts. Metagenomes from pristine, rural and urban sites in Australia were analyzed with AMR ++ and customized binning pipelines. AMR was present in all environments, while MR was mainly in rural and urban samples. AMR gene diversity was higher in rural and urban sites, exhibiting resistance to more antibiotic classes ( IMPORTANCE: Antimicrobial resistance (AMR) and metal resistance (MR) are critical global health concerns exacerbated by anthropogenic activities. The intricate mechanism underlying the interaction among anthropogenic activities, microbial communities, and resistance remains enigmatic. We developed novel bioinformatic pipelines to unveil this interaction in three aquatic environments. Our findings demonstrate the presence of specific bacterial communities that drive AMR and MR in rural and urban environments. This study underscores the significance of proper agricultural practices, comprehensive monitoring, and management strategies to reduce anthropogenic impacts on environmental resistance.

Indexed as

Anti-Bacterial AgentsBacteriaDrug Resistance, BacterialMetals, HeavyWater MicrobiologyWater Pollutants, ChemicalAustraliaDrug Resistance, Multiple, BacterialHuman ActivitiesHumansMetagenomeAnti-Bacterial AgentsMetals, HeavyWater Pollutants, Chemicalaquatic environmentsbacterial communitiesdrug resistancegenomicsresistance frequency

Identifiers

PMID40071918
PMCPMC12016542

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.